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Immunohistochemical study of primary gastrointestinal malignant lymphoma

Immunohistochemical study of primary gastrointestinal malignant lymphoma

Zhonghua Bing Li Xue Za Zhi 20(4): 254-256

63 cases of primary gastrointestinal non-Hodgkin's malignant lymphoma (ML), including 18 cases of gastric ML, 25 cases of small intestinal ML, 12 cases of ileocaecal ML and 8 cases of large intestinal ML, were studied. Small non-cleaved cell lymphomas were most common, accounting for 25.4% which was more common in the bowel than in the stomach. In 41 cases, a panel of monoclonal antibodies including L26, UCHL-1, Leu22 and Mac387 were used on paraffin section. The result of the staining was satisfactory in 37 cases. There were 35 cases (94.6%) exhibiting B-cell phenotype and 2 cases (5.4%) exhibiting T-cell phenotype. No histiocytic type was detected. The results of this and previous studies confirm the fact that most gastrointestinal lymphomas are B-cell lymphomas.

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Accession: 040363903

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PMID: 1813157

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