Immunostaining of eta cells in the rostral pars distalis and PAS-positive cells in the pars intermedia of a teleost (Sarotherodon mossambicus) by antisera to mammalian prolactins

Rawdon, B.B.

General and Comparative Endocrinology 37(3): 374-382

1979


ISSN/ISBN: 0016-6480
PMID: 378762
DOI: 10.1016/0016-6480(79)90011-x
Accession: 040370929

Download citation:  
Text
  |  
BibTeX
  |  
RIS

Article/Abstract emailed within 0-6 h
Payments are secure & encrypted
Powered by Stripe
Powered by PayPal

Abstract
Antisera to human, ovine and bovine prolactins (PRL) stained .eta. cells in the rostral pars distalis of S. mossambicus specifically. These observations support the view that the .eta. cells are the source of a PRL-like hormone which has antigenic determinants in common with mammalian PRL. Two of the antisera stained the periodic acid-Schiff (PAS)-positive cells in the pars intermedia as well as .eta. cells. Staining of both these cell types could be eliminated by absorption of the antisera with the appropriate PRL antigens. Either the secretory product of the PAS-positive cells shares antigenic determinants with mammalian PRL or the antibody which is staining these cells is directed against another peptide present as a contaminant in the antigen. Further experiments are needed to resolve this point.