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Isolation of CB-25-I, an antifungal antibiotic, from Serratia plymuthica



Isolation of CB-25-I, an antifungal antibiotic, from Serratia plymuthica



Journal of Antibiotics 42(6): 869-874



A new antifungal antibiotic, CB-25-I, was isolated from the culture broth of a strain of Serratia plymuthica. The antibiotic, a water-soluble dipeptide, is structurally related to Sch 37137 and A 19009, both produced by strains of Actinomycetales. The antibiotic exhibits inhibitory activity against Candida albicans in YNB medium (a synthetic medium), but the activity is significantly reduced in Sabouroud dextrose medium.

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Accession: 040521180

Download citation: RISBibTeXText

PMID: 2500411

DOI: 10.7164/antibiotics.42.869



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