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Life-threatening ventricular arrhythmia (torsades de pointes) after haloperidol overdose

Life-threatening ventricular arrhythmia (torsades de pointes) after haloperidol overdose

Human and Experimental Toxicology 10(1): 59-62

A 48-year-old woman developed QT prolongation and episodes of life-threatening ventricular tachycardia (torsades de pointes) after intentional overdose of haloperidol and orphenadrine. The arrhythmia did not respond to conventional anti-arrhythmic therapy but was suppressed by atrial overdrive pacing. A literature review identified haloperidol as the most likely cause of the torsades de pointes.

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Accession: 040574184

Download citation: RISBibTeXText

PMID: 1673626

DOI: 10.1177/096032719101000110

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