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Localization of acidic fibroblast growth factor (aFGF) mRNA in mouse and bovine retina by in situ hybridization

Jacquemin, E.; Halley, C.; Alterio, J.; Laurent, M.; Courtois, Y.; Jeanny, J.C.

Neuroscience Letters 116(1-2): 23-28

1990


ISSN/ISBN: 0304-3940
PMID: 1701865
DOI: 10.1016/0304-3940(90)90380-r
Accession: 040590231

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Acidic fibroblast growth factor (aFGF) mRNA has been detected in adult mouse or bovine retina by in situ hybridization with bovine aFGF cDNA clones. It is localized on ganglion cell layer, inner nuclear layer, photoreceptors and slightly on pigmented epithelium. This synthesis of aFGF in highly specialized retinal cell types is discussed in the framework on current views about the role of FGF in retinal cell biology.

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