+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Malignant transformation in non-irradiated recurrent respiratory papillomatosis



Malignant transformation in non-irradiated recurrent respiratory papillomatosis



Laryngoscope 95(8): 900-904



The clinical, radiographic and post mortem findings occurring in a 6-year-old female with a four-year history of recurrent respiratory papillomatosis (RRP) are described. At autopsy, there were two separate foci of malignant transformation (malignant degeneration) in the bronchioloalveolar papillomata. This patient is the youngest in whom such changes have been described. Malignant transformation is a rare occurrence and is usually seen in older patients with longstanding papillomatosis, therapeutic irradiation, or a history of smoking. Pulmonary spread represents the majority of cases with "spontaneous" malignant transformation.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 040630232

Download citation: RISBibTeXText

PMID: 4021682

DOI: 10.1288/00005537-198508000-00003


Related references

Recurrent respiratory papillomatosis with malignant transformation. Respirology 15(4): 726-7; Author Reply 727-8, 2010

Malignant Transformation In Recurrent Respiratory Papillomatosis. Chest 134(4): c58002-a-c58002-b, 2008

Recurrent respiratory papillomatosis with malignant transformation in a young adult. Respiratory Medicine 90(1): 53-55, 1996

Recurrent respiratory papillomatosis with lung involvement and malignant transformation. Thorax 69(3): 302-303, 2014

Unusual malignant transformation of juvenile recurrent respiratory papillomatosis. Otolaryngology--Head and Neck Surgery 136(2): 321-323, 2007

Remote intrapulmonary spread of recurrent respiratory papillomatosis with malignant transformation. Pediatric Pulmonology 39(2): 185-188, 2005

A Case of the Intrapulmonary Spread of Recurrent Respiratory Papillomatosis With Malignant Transformation. American Journal of the Medical Sciences 350(1): 55-57, 2015

Malignant Transformation of Recurrent Respiratory Papillomatosis: Atypical Presentation as Right Mainstem Bronchus Occlusion. Chest Journal 145(3): 478a-1-478a-2, 2014

Malignant transformation of recurrent respiratory papillomatosis associated with integrated human papillomavirus type 11 DNA and mutation of p53. Laryngoscope 108(5): 735-740, 1998

Malignant transformation of a highly aggressive human papillomavirus type 11-associated recurrent respiratory papillomatosis. American Journal of Otolaryngology 31(4): 291-296, 2010

Clinical-pathologic conference in general thoracic surgery: malignant transformation of recurrent respiratory papillomatosis. Journal of Thoracic and Cardiovascular Surgery 130(4): 1190-1193, 2005

'Papillomatization' and 'malignant transformation' of an abscess cavity in a 25-year old man with recurrent respiratory papillomatosis who may have had Lemierre syndrome. Chronic Respiratory Disease 1(4): 229-231, 2004

A case of video-assisted thoracoscopic resection of malignant transformation of pulmonary recurrent respiratory papillomatosis. Journal of Thoracic Disease 9(4): E364-E366, 2017

Incidence, age at onset, and potential reasons of malignant transformation in recurrent respiratory papillomatosis patients: 20 years experience. Otolaryngology--Head and Neck Surgery 132(3): 392-394, 2005

Rare case of malignant transformation of recurrent respiratory papillomatosis associated with human papillomavirus type 6 infection and p53 overexpression. Springerplus 2(1): 153, 2013