EurekaMag
+ Translate
+ Most Popular
Allopurinol and Loss of Consciousness in a 78-old Year Man Suffering from Gout
The parasites of British birds and mammals. 3XIV-3XVH
Studies on the in vitro synthesis of phi x 174 super helical covalently closed circular duplex dna and circular single stranded dna
The Shahada movement: a peasant movement in Maharashtra (India) - its development and its perspectives
The cranial nerves of Wallago attu
Anatomy of Mystus seenghala IV Nervous system
Haematology of Persian fallow deer (Dama mesopotamica)
Major weeds of rabi and kharif crops and their control
Structure of Morija-Banol iron-ore deposits, Rajasthan, and its control over mineralization
Donkioporia expansa - A lesser known wood destroyer in buildings
The new physiology of vision 3Xin. The testing of color-vision
Economic importance of Pteridophytes
Comparison of rice bran and maize bran as feeds for growing and fattening pigs
Ketoconazole shampoo 1% vs. climbazole shampoo in the treatment of seborrhoeic scalp dermatitis
Economic efficiency of biwall drip irrigation in sugarcane production - a case study in Ankalkhop village in Sangli District of Maharashtra
48,4X-49,5X mosaic: asynchronies among the late-replicating X chromosomes
Compatibility of potassium phosphonate (Akomin-40) with different species of Trichoderma and Gliocladium virens
Enterobacter amnigenus. An unusual human pathogen
The 48 4X 49 4Xy 49 4X iso chromosome yq mosaicism in a 3 year old boy from a twin pregnancy
Placentrex treatment in corneal defects in animals
The biology of human starvation: some new insights
Real-time PCR assays for the specific detection of monkeypox virus West African and Congo Basin strain DNA
Replenishable but depletable resources: water
New insights into bestiality and zoophilia
Thoracic outlet syndrome in Ehlers-Danlos patients as displayed by magnetic resonance imaging, angiography and venography

Monoamine metabolites in cerebrospinal fluid during treatment with clonidine or alprenolol


Monoamine metabolites in cerebrospinal fluid during treatment with clonidine or alprenolol



European Journal of Clinical Pharmacology 11(2): 125-128



ISSN/ISBN: 0031-6970

PMID: 837965

DOI: 10.1007/bf00562903

Lumbar cerebrospinal fluid (CSF) concentrations of the major metabolites of noradrenaline (4-hydroxy-3-methoxyphenyl glycol, HMPG), serotonin (5-hydroxyindoleacetic acid) and dopamine (homovanillic acid) were measured before and during the administration of clonidine or alprenolol to hypertensive patients. The noradrenaline receptor stimulant clonidine significantly decreased the CSF level of HMPG, but there was no consistent change in the concentration of serotonin or dopamine metabolites. Patients on alprenolol showed no change in the levels of these metabolites in CSF.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 040729143

Download citation: RISBibTeXText

Related references

Effects of oral clonidine premedication on concentrations of cortisol and monoamine neurotransmitters and their metabolites in cerebrospinal fluid and plasma. Acta Anaesthesiologica Scandinavica 33(2): 137-141, 1989

Monoamine metabolites in cerebrospinal fluid during treatment of hypertension with prazosin. European Journal of Clinical Pharmacology 18(5): 399-401, 1980

Changes of cerebrospinal fluid monoamine metabolites during long-term antidepressant treatment. European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology 10(5): 341-349, 2000

Monoamine metabolites in cerebrospinal fluid and serotonin uptake inhibition during treatment with chlorimipramine. Clinical Pharmacology and Therapeutics 21(2): 201-207, 1977

Monoamine metabolites in cerebrospinal fluid of depressed patients during treatment with mianserin or amitriptyline. Journal of Affective Disorders 4(3): 219-226, 1982

Lithium carbonate treatment of mania. Cerebrospinal fluid and urinary monoamine metabolites and treatment outcome. Archives of General Psychiatry 44(4): 345-354, 1987

Effect of ischemia on monoamine metabolism. Brain monoamine metabolites in cerebrospinal fluid of patients with recent cerebral infarction. Neuropatologia Polska 20(1-2): 97-105, 1982

Biochemical effects of antidepressant treatment--studies of monoamine metabolites in cerebrospinal fluid and platelet [3H]imipramine binding. Ciba Foundation Symposium 123: 57-83, 1986

Corticotropin releasing factor like immunoreactivity in cerebrospinal fluid in normal controls and major depression relationship to cerebrospinal fluid monoamine metabolites dexamethasone suppression test and trh stimulation test results. Society for Neuroscience Abstracts 10(2): 1093, 1984

Intravenous probenecid loading. Effects on plasma and cerebrospinal fluid probenecid levels and on monoamine metabolites in cerebrospinal fluid. Neurology 26(10): 992-996, 1976

Fluoxetine treatment of depression. Clinical effects, drug concentrations and monoamine metabolites and N-terminally extended substance P in cerebrospinal fluid. Acta Psychiatrica Scandinavica 79(6): 586-596, 1989

Effects of clomipramine treatment on cerebrospinal fluid monoamine metabolites and platelet 3H-imipramine binding and serotonin uptake and concentration in major depressive disorder. Acta Psychiatrica Scandinavica 83(2): 125-133, 1991

Cerebrospinal fluid monoamine metabolites and suicide. Nordic Journal of Psychiatry 61(3): 233-234, 2007

Purine and monoamine metabolites in cerebrospinal fluid. Advances in Experimental Medicine and Biology 195 Pt B: 53-56, 1986

Behavior of some monoamine metabolites in cat cerebrospinal fluid (CSF). Pharmacological Research 31: 273-273, 1995