Monoclonal antibodies to individual antigens of the nervous system of the snail, Helix pomatia

Pankova, T.M.; Starostina, M.V.; Shtark, M.B.

Biulleten' Eksperimental'noi Biologii i Meditsiny 110(9): 289-290


ISSN/ISBN: 0365-9615
PMID: 2268718
Accession: 040730598

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Seven positive hybridoma clones were chosen by immunoenzyme analysis amons 103 clones obtained by hybridization of NSO plasmocytoma cells and splenocytes from BALB/C mice, immunized with snail's nervous system antigens. Specific binding of Mabs with neuron cytoplasmic antigens was indicated on cryostat sections of visceral, pedal and cerebral ganglia. The Mabs obtained could be used for the study of physiological role of antigens identified.