+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Neonatal apnea: underlying disorders



Neonatal apnea: underlying disorders



Pediatrics 63(1): 8-12



Data from a prospective study of 50,826 neonates were used to determine the frequency and significance of disorders related to apnea in newborns. Such apnea proved to be a significant prognosticator for neonatal death. Fifty-eight percent of preterm neonates with multiple apneic episodes and 18% with a single episode died, whereas only 6% of those without recorded apnea died. The rates were 44%, 5%, and 1% for full-term infants. Amniotic fluid infection was the underlying disorder in 35% of the preterm and 25% of the term neonates who had multiple episodes of apnea. A third of the preterm and 25% of the term infants who had such apneic episodes had antecedent hypoxia-related disorders, i.e., abruptio placentae, erythromblastosis fetalis, placenta previa, large placental infarcts, and umbilical cord compression. Among the apneic neonates, those who were infected were twice as apt to die as were those who had hypoxia-related disorders. Hypoplasia of the lungs and easily recognized central nervous system malformations were responsible for most of the apnea-related deaths associated with congenital malformations.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 040780433

Download citation: RISBibTeXText

PMID: 571597


Related references

Underlying disorders responsible for the neonatal deaths associated with low Apgar Scores. Biology of the Neonate 35(3-4): 150-155, 1979

Methods for treating apnea, apnea disorders, bulimia, and other disorders using optically pure norcisapride. Official Gazette of the United States Patent and Trademark Office Patents 1233(2), 2000

Neonatal apnea casebook. Gastroesophageal reflux (GER)-associated apnea. Journal of Perinatology 19(1): 77-79, 2000

Epidemiology of neonatal acute respiratory disorders. A multicenter study on incidence and fatality rates of neonatal acute respiratory disorders according to gestational age, maternal age, pregnancy complications and type of delivery. Italian Group of Neonatal Pneumology. Biology of the Neonate 74(1): 7-15, 1998

Methods for treating apnea and apnea disorders using optically pure R ondansetron. Official Gazette of the United States Patent and Trademark Office Patents 1269(3), 2003

Obstructive sleep apnea in epilepsy patients: the Sleep Apnea scale of the Sleep Disorders Questionnaire (SA-SDQ) is a useful screening instrument for obstructive sleep apnea in a disease-specific population. Sleep Medicine 4(6): 517-521, 2003

Pathophysiologic Mechanisms Underlying Apnea of Prematurity. Neoreviews 3(4): 59e-65, 2002

What is the underlying pathology of sleep apnea associated-erectile dysfunction?. Journal of Urology 161(4 Suppl. ): 270, 1999

Exploration of potential mechanisms underlying substance use disorders in individuals with personality disorders. Sante Mentale au Quebec 39(2): 99-115, 2015

A proposed mechanism underlying eating disorders and other disorders of motivated behavior. Andersen, A E (Ed ) Brunner/Mazel Eating Disorders Monographs Series, No 4 Males With Eating Disorders X+264p Brunner/Mazel Publishers: New York, New York, Usa Illus 221-254, 1990

Early apnea in the term newborn is associated with serious but treatable underlying conditions. Pediatric Research 25(4 Part 2): 210A, 1989

Obstructive sleep apnea and dyslipidemia: evidence and underlying mechanism. Sleep and Breathing 18(1): 13-18, 2014

Obstructive sleep apnea in epilepsy patients Further validation of the Sleep Apnea Scale of the Sleep Disorders Questionnaire in a disease-specific population. Sleep 24(Abstract Suppl.): A271-A272, 2001

Concordance of genetic variation that increases risk for anxiety disorders and posttraumatic stress disorders and that influences their underlying neurocircuitry. Journal of Affective Disorders 245: 885-896, 2019

Mechanisms Underlying Improvement in Obstructive Sleep Apnea Syndrome by Uvulopalatopharyngoplasty. Case Reports in Otolaryngology 2017: 2120165, 2017