+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Neonatal hyperbilirubinaemia following the use of oxytocin in labour

Neonatal hyperbilirubinaemia following the use of oxytocin in labour

British Journal of Obstetrics and Gynaecology 82(4): 265-271

A prospective study of 1353 labours and the relevant newborn failed to reveal any significant difference between the incidence of neonatal hyperbilirubinaemia (defined as a level of 12 mg. or more per 100 ml.) following spontaneous labour, and after labour induced or accelerated by oxytocin. The incidence of unexplained neonatal hyperbilirubinaemia after spontaneous labour was 6-3 per cent. Following induced labour however there was a highly significant (P less than 0-001) association between the mean total dose of oxytocin used for induction and the incidence of neonatal hyperbilirubinaemia. The proportion of babies who developed hyperbilirubinaemia increased in direct relation to the total dose of oxytocin used for the induction. In this series the incidence of hyperbilirubinaemia increased sharply when the total dose of oxytocin exceeded 20 units as it did hyperbilirubinaemia and birthweight, or duration of spontaneous labour. When labour was induced, however, the proportion on newborn babies with hyperbilirubinaemia increased with the duration of labour. The significance of these findings is discussed.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 040780974

Download citation: RISBibTeXText

PMID: 1125148

DOI: 10.1111/j.1471-0528.1975.tb00632.x

Related references

Pathogenesis of neonatal hyperbilirubinaemia after induction of labour with oxytocin. British Medical Journal 2(6200): 1255-1257, 1979

Oxytocin induction and neonatal hyperbilirubinaemia. British Medical Journal 2(6093): 1028, 1977

Neonatal hyperbilirubinaemia following the use of prostaglandin E2 in labour. British Journal of Obstetrics and Gynaecology 83(1): 62-67, 1976

Oxytocin challenge test and neonatal hyperbilirubinaemia. Lancet 2(7993): 1026, 1976

Pathogenesis of oxytocin-induced neonatal hyperbilirubinaemia. Archives of Disease in Childhood 54(5): 400-402, 1979

Neonatal hyperbilirubinaemia: a comparison between prostaglandin E2 and oxytocin inductions. British Medical Journal 2(6088): 679-680, 1977

Hyperbilirubinaemia in neonatal rats after oxytocin or prostaglandin F2 alpha treatment of pregnant rats. Biology of the Neonate 47(5): 288-294, 1985

Oxytocin infusion during labour and neonatal jaundice. Indian Pediatrics 15(5): 399-402, 1978

Neonatal hyperbilirubinemia in oxytocin augmented labour. Asia-Oceania Journal of Obstetrics and Gynaecology 11(1): 69-73, 1985

The effect of oxytocin in induced labour on neonatal jaundice. British Journal of Obstetrics and Gynaecology 86(2): 133-138, 1979

Oxytocin induction of labour: hyponatraemia and neonatal jaundice. European Journal of Obstetrics & Gynecology & Reproductive Biology 22(5-6): 309-318, 1986

Neonatal jaundice in association with oxytocin stimulation of labour and operative delivery. British Medical Journal 1(6003): 198-199, 1976

Birth weight, and use of oxytocin and analgesic agents in labour in relation to neonatal jaundice. Medical Journal of Australia 2(10): 466-469, 1982

Changes in neonatal transcutaneous bilirubinometer index following intravenous fluid and oxytocin infusion during labour. Asia-Oceania Journal of Obstetrics and Gynaecology 14(4): 411-414, 1988

A case-control study on the relationship between neonatal hyperbilirubaemia and usage of oxytocin during labour. Zhonghua Liu Xing Bing Xue Za Zhi 13(5): 294-296, 1992