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Nodular regenerative hyperplasia of the liver and primary biliary cirrhosis. A fortuitous association?



Nodular regenerative hyperplasia of the liver and primary biliary cirrhosis. A fortuitous association?



Gastroenterologie Clinique et Biologique 10(11): 764-766



We report here in a case of primary biliary cirrhosis associated with nodular regenerative hyperplasia of the liver in a white woman revealed by digestive hemorrhage due to ruptured esophageal varices. The diagnosis of primary biliary cirrhosis was based on the following: elevated serum IgM, high titer of antimitochondrial antibody (anti M2), typical histopathological picture of stage I/II disease. The diagnosis of nodular regenerative hyperplasia was supported by the demonstration of disseminated small hepatic nodules without perinodular fibrosis. This association may be a supplementary argument in favor of a possible autoimmune origin of nodular regenerative hyperplasia of the liver.

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Accession: 040810595

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PMID: 3803811


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