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Radiation-induced cerebrovascular disease in children

Radiation-induced cerebrovascular disease in children

Neurology 26(6 Pt 1): 540-543

Radiation-induced internal carotid artery occlusion has not been well recognized previously as a cause of childhood cerebrovascular disease. A child who had received radiation as a neonate for a hemangioma involving the left orbit at the age of 6 years experienced a recurrent right-sided paresis, vascular headaches, and speech difficulties. Angiography showed a hypoplastic left carotid artery with occlusion of both the anterior and middle cerebral arteries. Collateral vessels bypassed the occluded-stenotic segments. Review of the literature showed two additional cases of large vessel occlusion in childhood associated with anastomatic telangiectatic vessel developmental following early radiation therapy of facial hemangioma.

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Accession: 041159169

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PMID: 945495

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