+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Radiation-induced decomposition of the purine bases within DNA and related model compounds



Radiation-induced decomposition of the purine bases within DNA and related model compounds



International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine 47(2): 127-143



This survey focuses on recent developments in the radiation chemistry of purine bases in nucleic acids and related model compounds. Both direct and indirect effects of ionizing radiation are investigated with special emphasis on the structural characterization of the final decomposition products of nucleic acid components. Available assays for monitoring radiation-induced base lesions are critically reviewed.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 041159229

Download citation: RISBibTeXText

PMID: 2984127

DOI: 10.1080/09553008514550201


Related references

The radiation chemistry of the purine bases within DNA and related model compounds. Basic Life Sciences 38: 69-74, 1986

Hydroxyl and one-electron oxidation mediated reactions of the purine bases of DNA and model compounds Mechanistic aspects. Fuciarelli, A F , Zimbrick, J D Radiation damage in DNA: Structure/function relationships at early times 305-312, 1995

Determination of purine compounds and purine bases in food. Zeitschrift für Lebensmittel-Untersuchung und -Forschung 185(4): 288-291, 1987

The quantitative determination of metabolites of 6 mercapto purine in biological materials part 4 an improved separation method for 22 compounds related to purine and 6 thio purine metabolism using high pressure liquid cation exchange chromatography. Zeitschrift fuer Naturforschung Section C Journal of Biosciences 32(11-12): 905-907, 1977

Energy Increment Method Based on Quantum Chemical Results: A General Recipe for Approximative Prediction of Isomerization and Tautomerization Energies of Pyrimidine and Purine Nucleic Acid Bases and Related Compounds. Journal of Physical Chemistry A 103(33): 6612-6623, 1999

Radiation-induced decomposition of DNA as an experimental model for the estimation of the activity of substances protecting against radiation. Dokl Akad Nauk Sssr 157(4): 979-981, 1964

Radiation induced decomposition of halogenated organic compounds in water. Radiation Physics and Chemistry 52(1-6): 327-331, 1998

Effect of ethanol ingestion on nucleotides and glycolytic intermediates in erythrocytes and purine bases in plasma and urine: Acetaldehyde-induced erythrocyte purine degradation. Metabolism Clinical and Experimental 42(9): 1212-1216, 1993

Thermal decomposition of model compounds related to branched 4-O-methylglucuronoxylans. Carbohydrate research 70(2): 199-207, 1979

Radiation chemistry of purine bases. Radiation Research 70(3): 648, 1977

Radiation induced binding of high molecular compounds in living cell with amino acids and bases. Journal of Radiation Research 14(1): 91, 1973

Characterizing substrate properties of purine-related compounds with purine metabolism enzymes for enzymatic peak-shift HPLC method. Nucleosides Nucleotides and Nucleic Acids 33(4-6): 445-453, 2014

Studies on the analysis of purine and pyrimidine bases of nucleic acid. III. A spectrophotometric method for analysis of the purine and pyrimi-dine bases in DNA. Acta Biochim Biophys Sinica 3(1): 74-79, 1963

Analysis of radioactive and nonradioactive purine bases, purine nucleosides and purine nucleotides by high-speed chromatography on a single column. Monographs in Human Genetics 10: 127-134, 1978

Studies on the metabolism of model compounds related to soil humic acid. L The decomposition of N- glycine. Australian J Biol Sci 17(1): 153-169, 1964