+ Site Statistics
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
EurekaMag PDF Full Text Supply ServicePDF Full Text Supply Service
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn
Follow on LinkedInFollow on Tumblr

+ Translate

Regulation of glycogen synthase interconversion in cultured muscle cells: actions of insulin, calcium, ionophore A 23187 and cytochalasin B

, : Regulation of glycogen synthase interconversion in cultured muscle cells: actions of insulin, calcium, ionophore A 23187 and cytochalasin B. Molecular and Cellular Endocrinology 8(1): 35-46

The glycogen content of cultured chick embryo breast muscle cells changes during their development and can be reduced by starvation. It is demonstrated that the rate of glucose incorporation into glycogen and the degree of interconversion of glycogen synthase are controlled by the actual glycogen content. Stimulation of both corresponding activities by insulin is found in fused and in unfused cells. The insulin response depends on the extracellular calcium concentration and can be mimicked by the ionophore A 23187. These metabolic effects as well as calcium efflux data confirm the hypothesis that insulin acts on its enzyme target via increased cytoplasmic calcium concentration. Cytochalasin B is shown to inhibit the interconversion but does not interfere with the insulin-induced increase of the mitochondrial calcium pool or with the acceleration of the calcium efflux out of 45C-preloaded myotubes.

(PDF 0-2 workdays service)

Order PDF Full Text


Click here to order any other PDF Full Text

Accession: 041210787

PMID: 407113

PDF Full Text: Submit

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Other references

Wallis P.J.W.; Few J.D.; Newland A.C.; Empey D.W., 1985: Effects of reversing polycythemia on renal hemodynamics and the renin angiotensin system in hypoxic cor pulmonale. American Review of Respiratory Disease 131(4 SUPPL): A58

Miner, John R., 1945: Some uses of statistical methods in medicine. Statistical studies have been used to demonstrate the relationship between previous case history and the incidence of certain human diseases. The use of the statistical method in determining the most efficient criteria for interpreting diagnostic...

Munavalli, S.; Rossman, D. I.; Rohrbaugh, D. K.; Ferguson, C. P.; Buettner, L., 1993: Synthesis and biological screening of trifluoromethylthioarsenicals. The title compounds have been prepared from the reaction of trifluoromethylthiocopper and alkyl mono- and di-haloarsines. This communication describes their synthesis, biological screening and mass spectral fragmentation behavior.

Zaki, FN.; Gesraha, MA., 1987: Evaluation of zertel and diflubenzuron on biological aspects of the egg parasitoid, Trichogramma evanescens Westw. and the aphid lion Chrysoperla carnea Steph. The anti-moulting compounds diflubenzuron and Zertel 439 [2-chloro-N-[[[4-(2,2-dichloro-1,1-difluoroethoxy)phenyl]amino]carbonyl]benzamide] showed adverse effects on the egg parasitoid Trichogramma evanescens (reared on Anagasta kuehniella [Ephest...

Limbert, M., 1991: Further notes on the bog bush-cricket Metrioptera brachyptera in Yorkshire. Yorkshire Naturalists Union Bulletin, 1-2 No. 15

Roets, Sd, 1982: A system developed for the treatment of tanning and other prteinaceous effluents South Africa. Water science and technology4(9-11): 1547-1548

Singh, JP.; Mukesh, Devinder.; Shashi, A., 1996: Embryonic development of circulatory system in Aulacophora foveicollis Lucas (Coleoptera: Chrysomelidae). In the early embryonic development of Aulacophora foveicollis, the heart and aortia were derived from the special cells, the cardioblasts which developed from the dorso-lateral walls of all the coelomic sacs from the last abdominal segment to the...

Movsesyan, T. B.; Karakhanyan, S. G., 1975: Patho morphology of olfactory bulbs of the brain in contagious agalactia of sheep. In contagious agalactia of sheep, serous meningoencephalitis develops in the CNS; the olfactory bulbs of the brain are also pathomorphologically sensitive.

Hittelman Allen M.; Lockridge Patricia A.; Whiteside Lowell S.; Lander James F., 2001: Interpretive pitfalls in historical hazards data. Natural Hazards 23(2-3): 315-338

Walter, C., 1987: How do I pierce ears for earrings?. Laryngologie, Rhinologie, Otologie 66(3): 161-161