+ Site Statistics
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
EurekaMag PDF Full Text Supply ServicePDF Full Text Supply Service
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn
Follow on LinkedInFollow on Tumblr

+ Translate

Regulation of hepatitis B virus S gene promoter in transfected cell lines

, : Regulation of hepatitis B virus S gene promoter in transfected cell lines. Virology 162(2): 362-368

Hepatitis B virus (HBV) contains an enhancer element that activates the viral core and X gene promoters. To investigate the transcriptional regulation of the viral S gene promoter, we transfected SK-Hep1 cells with circularized forms of HBV DNAs and their enhancerless mutants. We have found that expression of the S gene, determined by measurement of the appearance of HBsAg in the media and by RNA analysis, is to a large extent enhancer-dependent. This observation was further confirmed by analysis of a series of plasmids containing the chloramphenicol acetyl-transferase (CAT) gene under the control of the S gene promoter and the HBV enhancer element. Interestingly, in contrast to its behavior in SK-Hep1 cells, the S gene promoter is highly active in Alexander cells, in the absence of the enhancer element. This implies that activity of the S gene promoter is cell-type specific.

(PDF 0-2 workdays service)

Order PDF Full Text


Click here to order any other PDF Full Text

Accession: 041210979

PMID: 3422523

PDF Full Text: Submit

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Other references

FEHRER, E., 1951: Latent learning in the sophisticated rat. This expt. tests the assumption that the difficulty in demonstrating latent learning in the rat may be due in part to the fact that naive animals have been used. It was assumed that learning the location of objects such as food pellets will not oc...

Alavaikko M., 1974: Value of free metaphase cell preparations in cyto photometric study of experimental skin carcinogenesis. Acta Pathologica et Microbiologica Scandinavica Section A Pathology 82(1): 145-152

Novotny, V.; Capodaglio, A.; Jones, H., 1992: Real Time Control of wastewater treatment operations. Water Science & Technology 25(4-5): 89-101

Dao, M. A.; Nolta, J. A., 1997: Improvement in retroviral-mediated transduction of quiescent human hematopoietic progenitors through a combination of TGFbeta neutralization and antisense oligonucleotides to the CDK inhibitor P27kip-1. Blood 90(10 SUPPL 1 PART 1): 600A, Nov 15

Ribeyre, F.; Boudou, A., 1984: Etude experimentale des processus de decontamination chez Salmo gairdneri, apres contamination par voie directe avec deux derives du mercure (HgCl2 et CH3HgCl)- analyse des transferts aux niveaux 'organisme' et 'organes'. Environmental Pollution Series A, Ecological and Biological 35(3 ): 3-28

Torrisani, Jerome; Bouisson, Michele; Puente, Elena; Capella, Gabriel; Laurent Puig, Pierre; Vaysse, Nicole; Susini, Christiane; Buscail, Louis, 2000: Transcription of sst2 somatostatin receptor gene is altered by promoter polymorphism in human pancreatic cancer cells. Gastroenterology 118(4 Suppl 2 Part 1): AGA A711, April

Grussendorf-Conen, E.I., 1992: Age-dependent therapeutic response of plantar warts. Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und Verwandte Gebiete 43(7): 458-458

Broda P.; Birch O.; Brown A.; Haylock R.; Liwicki R.; Macdonald M.; Paterson A.; Raeder U.; Schrank A.; Sims P., 1986: Lignin degradation and its control in phanerochaete chrysosporium. Heredity 57(1): 140

Ueno, K.; Saha, A.R.; Kitagawa, H.; Satoh, T., 1990: Effects of heptaminol AMP amidate (HAA) on cyclic AMP level and mitogen-induced proliferation of murine spleen cells. Heptaminol AMP amidate (HAA), a nucleotide derivative, was found to elevate the intracellular cyclic AMP (cAMP) level of cultured mice spleen cells in a time- and dose-dependent manner. Theophylline and imidazole, when added to the spleen cell cul...

Lagervall, G.Z., 1975: Practical nurses in nursing service. Tidskrift for Sveriges Sjukskoterskor 42(11): 57-57