+ Site Statistics
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
EurekaMag PDF Full Text Supply ServicePDF Full Text Supply Service
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn
Follow on LinkedInFollow on Tumblr

+ Translate

Regulation of hypoxanthine transport in Neurospora crassa

, : Regulation of hypoxanthine transport in Neurospora crassa. Journal of Bacteriology 128(2): 598-603

Hypoxanthine uptake and hypoxanthine phosphoribosyltransferase activity (EC were determined in germinated conidia from the adenine auxotrophic strains ad-1 and ad-8 and the double mutant strain ad-1 ad-8. The mutant strain ad-1 appears to lack aminoimidazolecarboximide ribonucleotide formyltransferase (EC or inosine 5'monophosphate cyclohydrolase (EC activities, or both, whereas the ad-8 strain lacks adenylosuccinate synthase activity (EC Normal (or wild-type) hypoxanthine transport capacity was found to the ad-1 conidia, whereas the ad-8 strains failed to take up any hypoxanthine. The double mutant strains showed intermediate transport capacities. Similar results were obtained for hypoxanthine phosphoribosyl-transferase activity assayed in germinated conidia. The ad-1 strain showed greatest activity, the ad-8 strain showed the least activity, and the double mutant strain showed intermediate activity levels. Ion-exchange chromatography of the growth media revealed that in the presence of NH+/4, the ad-8 strain excreted hypoxanthine or inosine, the ad-1 strain did not excrete any purines, and the ad-1 ad-8 double mutant strain excreted uric acid. In the absence of NH+/4, none of the strains excreted any detectable purine compounds.

(PDF 0-2 workdays service)

Order PDF Full Text


Click here to order any other PDF Full Text

Accession: 041211166

PMID: 135758

PDF Full Text: Submit

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Other references

Jacobsen, Odd W.; Ugelvik, Morten, 1998: Nest habitat of Eurasian wigeon Anas penelope in SW Norway. This paper describes nest habitats of Eurasian wigeon Anas penelope in SW Norway. 9 out of 11 nests were found in heather predominantly covered by Calluna vulgaris. Heather was selected as a nest habitat according to its availability, whereas scru...

Okusaka, T.; Okada, S.; Nose, H.; Ishii, H.; Nakasuka, H.; Nakayama, H.; Nagahama, H.; Yoshimori, M.; Shimada, K.; Yamamoto, J.; Takayama, T.; Kosuge, T.; Yamasaki, S.; Sakamoto, M.; Hirohashi, S., 1996: The prognosis of patients with hepatocellular carcinoma of multicentric origin. Background/Aims: The characteristics of patients with multicentric hepatocellular carcinoma (HCC) differ from those of patients with intrahepatic metastatic HCC. However, there are few reports regarding the long-term results in patients with HCC o...

Higatsberger M.R.; Auff E., 1984: Gangliosides in rabbit and human skeletal muscle with de nervation atrophy. In experimental denervation of rabbit skeletal muscle, an increase of gangliosides was reported. Ganglioside, DNA, total lipid and protein levels were studied in experimental denervation of rabbit gastrocnemius muscle and in human skeletal muscle...

Tibben, C.; Massuger, L.; Boerman, O.; Claessens, R.; Borm, G.; Warnaar, S.; Pak, K.; Koenders, E.; Corstens, F. H. M., 1993: Reduced kidney uptake of technetium-99M-labelled FAB fragments in an animal model using a cleavable chelator. Journal of Nuclear Medicine 34(5 SUPPL ): 247P

Falagan, A.; Garcia de Siles, J. L., 1986: Effect of sire breed on the performance of Aragon commercial crossbred lambs. 1. Growth traits. For 26 Mutton Merino X Aragon, 46 Charmoise X Aragon, 38 Ile-de-France X Aragon, and 29 Texel X Aragon lambs, gestation length averaged 151.99+or-0.48, 149.27+or-0.39, 150.08+or-0.35 and 148.83+or-0.40 days resp., and birth weight 3.16+or-0.15, 2....

Swier, Stanley R.; Rollins, Alan, 1996: Control of annual bluegrass weevil with pyrethroids, 1995. Burditt, A K , Jr [Editor] Arthropod Management Tests 342-343

Brand, Tv., 1937: Beobachtungen uber den Kohlehydratstoffwechsel einiger Turbellarien. Int Congr Zool, 12: 739-741

Grushka, M., 1987: Clinical features of burning mouth syndrome. A study was carried out to compare the clinical features of 102 subjects suffering from burning mouth syndrome (BMS) and 43 age- and sex-matched control subjects. In comparison with those in the control group, the BMS subjects reported a significa...

Wiiczek, M., 1963: The temperature preferendum of the wingless insects Onychiurus armatus Tullb. and Sinetta coeca Schott. (Apterygota, Collembola). Pr Zool Krakow, 8: 141-160

Persson, C.G.; Andersson, M.; Greiff, L.; Svensson, C.; Erjefält, J.S.; Sundler, F.; Wollmer, P.; Alkner, U.; Erjefält, I.; Gustafsson, B., 1995: Airway permeability. Clinical and Experimental Allergy 25(9): 807-814