EurekaMag.com logo
+ Site Statistics
References:
48,253,228
Abstracts:
22,798,842
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
EurekaMag PDF Full Text Supply ServicePDF Full Text Supply Service
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn
Follow on LinkedInFollow on Tumblr

+ Translate

Regulation of lactate/pyruvate ratios by cyclic AMP in Neurospora crassa


, : Regulation of lactate/pyruvate ratios by cyclic AMP in Neurospora crassa. Biochemical and Biophysical Research Communications 150(1): 365-370

Cyclic AMP is thought to have a general role in stimulating the breakdown of carbohydrate reserves and subsequent glycolytic activity. This would be expected to increase the availability of reducing equivalents in the form of cytoplasmic NADH. The current study examines another potential reaction controlling cytoplasmic NADH in the fungus Neurospora crassa, that of lactate dehydrogenase, to determine whether it is also regulated by cyclic AMP. The cr-1, adenylate cyclase and cyclic AMP-deficient mutant, grown with and without exogenous cyclic AMP was compared with an isogenic wild type. The results show that cyclic AMP raises pyruvic acid pools and lowers both lactic acid pools and lactate/pyruvate ratios. It does that, in part or in whole, by lowering lactate dehydrogenase activity. The possibility that cytoplasmic NAD+/NADH is a major target of cyclic AMP control is discussed. The high performance liquid chromatography procedures used in these studies are applicable to the measurement of intracellular pools of tricarboxylic acid cycle and other organic acids.

(PDF 0-2 workdays service)

Order PDF Full Text

Close
Close

Click here to order any other PDF Full Text


Accession: 041211481

PMID: 2827675

PDF Full Text: Submit


Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:
Close
Close

Other references

Anonymous, 1996: Deporaus marginellus.. A new distribution map is provided for Deporaus marginellus (Faust) Coleoptera: Curculionoidea, Attelabidae mango leaf-cutting weevil, mango funnel-rolling weevil. Attacks mango. Information is given on the geographical distribution in ASIA, Andam...

Rasch, E.K.; Gulley, S.P.; Chan, L., 2013: Use of emergency departments among working age adults with disabilities: a problem of access and service needs. To examine the relationship between emergency department (ED) use and access to medical care and prescription medications among working age Americans with disabilities.Data SourcePooled data from the 2006 2008 Medical Expenditure Panel Survey (MEP...

Crane, W. J. B., 1982: Computing grassland and forest fire behaviour, relative humidity and drought index by pocket calculator. A program is described that enables easy rapid field calculation of McArthur's fire danger indices [see FA 28, 5795; 29, 4037], a hazard rating and other measures of fire behaviour, together with rederived ancillary computations of RH and a d...

Pinkard, E. A.; Mohammed, C.; Beadle, C. L.; Hall, M. F.; Worledge, D.; Mollon, A., 2004: Growth responses, physiology and decay associated with pruning plantation-grown Eucalyptus globulus Labill. and E. nitens (Deane and Maiden) Maiden. Detailed studies have been undertaken to define pruning regimes for Eucalyptus nitens, but little is known of E. globulus responses to pruning although this is a more commonly planted species. This paper describes experiments that aimed to identif...

Tannirandorn, Yuen; Romayanan, Orasri, 1999: Fetomaternal hemorrhage after midtrimester genetic amniocentesis at King Chulalongkorn Memorial Hospital. Midtrimester genetic amniocentesis has become an accepted part of modern obstetric care. Although its accuracy is well established, the risk of fetomaternal hemorrhage remains controversial. This prospective study was conducted to determine how ef...

Hsieh, Yao-Ching; Chen, Shih-Hui; Chuang, Wei-Chao; Lee, Yen-Feng; Tsai, Keng-Yu; Tsai, Shinn-Shyong, 2005: Case report: Bovine ephemeral fever. Outbreak of bovine ephemeral fever (BEF) have recorded seven times in Taiwan. Recurrence was recently found in Tainan county in August 2004. From August 23 to September 30, we carried out an epidemiological survey on 128 farms which contained 23,3...

Heremans, H.; Dillen, C.; Groenen, M.; Matthys, P.; Billiau, A., 2000: Role of interferon-gamma and nitric oxide in pulmonary edema and death induced by lipopolysaccharide. Mice given lipopolysaccharide (LPS) intravenously developed lung edema, which was maximum after 6 h. Tumor necrosis factor, interleukin 12 (IL-12), IL-6, and interferon-gamma (IFN-gamma) appeared in the serum, and levels of nitrogen oxide (NO) der...

Zhong Heng; Xie YongQuan; Liu MeiLing; Zhang YiShun, 1995: Accumulative effect of Chlamydomonas and Tribonema in waste water of sulphate of copper. Chlamydomonas adapted to growing in waste water containing 525 mg/litre copper sulfate accumulated 41.63, 34.92 and 10.09% copper, iron and zinc, resp. The number of cells of Chlamydomonas present was positively correlated with the ionic content o...

Heman-Ackah, Y.D.; Sataloff, R.T., 2005: Use of silicone hearing aid mold material in laryngotracheal reconstruction. Objectives: Endolaryngeal stenting in patients with irregularly shaped larynges can be challenging. In such cases, the use of a moldable yet reasonably rigid endolaryngeal stent is desirable. The purpose of this report is to describe our experienc...

Tanoiri, Takashi; Nomoto, Jun; Yoshitake, Noriaki; Mogi, Junichi; Nakajima, Kazuhiko; Komatsu, Chikayoshi; Okamura, Tetsuo, 1993: Splitting of multicomponent high-frequency high right atrial potentials in atrial flutter with rapid pacing and their change into double potentials associated with shift to another atrial flutter. Japanese Circulation Journal 57(7): 738