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Specificity of the digoxin radioimmunoassay with respect to dihydrodigoxin


, : Specificity of the digoxin radioimmunoassay with respect to dihydrodigoxin. Research Communications in Chemical Pathology and Pharmacology 14(1): 83-88

An investigation was conducted to determine the specificity of the digoxin antibody provided in a commercially available radioimmunoassay kit with respect to dihydrodigoxin. Over the concentration range of 0.5 to 8.0 ng./ml. dihydrodigoxin displaced the 125I digoxin derivative from the antibody to a degree that could be significant at clinically observed serum and urine digoxin concentrations.

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Accession: 041408296

PMID: 935656

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Other references

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Adams Frank Dawson, 1915: Memoir of Alfred Ernest Barlow. Geological Society of America Bulletin Pages 12-18

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Fuller, M. E.; Lowey, J. M.; Schaefer, C. E.; Steffan, R. J., 2005: A peat moss-based technology for mitigating residues of the explosives TNT, RDX, and HMX in soil. There is increased interest in how to balance military preparedness and environmental protection at Department of Defense (DoD) facilities. This research evaluated a peat moss-based technology to enhance the adsorption and biodegradation of explos...