+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Studies on juvenimicin, a new antibiotic. II. Isolation, chemical characterization and structures



Studies on juvenimicin, a new antibiotic. II. Isolation, chemical characterization and structures



Journal of Antibiotics 29(11): 1171-1181



A series of new macrolide antibiotics was isolated from the culture filtrate of Micromonospora chalcea var, izumensis. The fat-soluble basic complex consisted of eight components which were named juvenimicin A1 approximately A4 and B1 approximately B4. Juvenimicin A3 was found to be identical with rosamicin and the structures of four of the other components (JVM A2, A4, B1 and B3) have been elucidated. Juvenimicin A2 has a methyl group at position 6 instead of the formylmethyl group of juvenimicin A3. Juvenimicin A4, B1 and B3 possess a hydroxyethyl group at position 6. Juvenimicin A4 and B1 differ from each other in the nature of the chromophore. Juvenimicin B3 differs from juvenimicin B1 in that a hydroxymethyl group is present at position 14 in the former.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 041460223

Download citation: RISBibTeXText

PMID: 993104

DOI: 10.7164/antibiotics.29.1171


Related references

Studies on juvenimicin a new antibiotic part 2 isolation chemical characterization and structures. Journal of Antibiotics 29(11): 1171-1181, 1976

Studies on juvenimicin, a new antibiotic. I. Taxonomy, fermentation and antimicrobial properties. Journal of Antibiotics 29(11): 1163-1170, 1976

Studies on juvenimicin a new antibiotic part 1 taxonomy fermentation and anti microbial properties. Journal of Antibiotics 29(11): 1163-1170, 1976

Studies on a new nucleoside antibiotic, dapiramicin. II. Isolation, physico-chemical and biological characterization. Journal of Antibiotics 37(1): 1-5, 1984

Antibiotic mdl 63766 a novel antifungal antibiotic discovery isolation biological and physico chemical characterization. Program & Abstracts of the Interscience Conference on Antimicrobial Agents & Chemotherapy 31: 133, 1991

I-11, a new antibiotic. Taxonomy of the strain I-11, isolation, fermentation, biological activity and chemical characterization of the antibiotic produced. Journal of Antibiotics 33(7): 754-757, 1980

Studies on antibiotic SF-837, a new antibiotic. I. The producing microorganism and isolation and characterization of the antibiotic. Journal of Antibiotics 24(7): 452-459, 1971

Studies on antibiotic SF-733, a new antibiotic. I. Taxonomy, isolation and characterization. Journal of Antibiotics 23(3): 155-161, 1970

Isolation, characterization and structures of new antibiotic components produced by fungal culture 07F275. Official Gazette of the United States Patent & Trademark Office Patents 1213(1): 669, 1998

Thiostrepton, a new antibiotic. II. Isolation and chemical characterization. Antibiotics Annual 3: 560-561, 1955

Elaiomycin, a new tuberculostatic antibiotic; isolation and chemical characterization. Antibiotics and ChemoTherapy 4(2): 141-144, 1954

A new antibiotic: bromotetracycline. I. Isolation and chemical and physical characterization. Il Farmaco; Edizione Scientifica 10(6): 337-345, 1955

Elaiomvcin, a new tuberculostatic antibiotic. Isolation and chemical characterization. Antibiot And Chemother 4(2): 141-144, 1954

Mersacidin, a new antibiotic from Bacillus. Fermentation, isolation, purification and chemical characterization. Journal of Antibiotics 45(6): 832-838, 1992

Lipiarmycin, a new antibiotic from Actinoplanes. II. Isolation, chemical, biological and biochemical characterization. Journal of Antibiotics 28(4): 253-259, 1975