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Teichoic acid from the cell wall of Actinomadura carminata--a producer of the antibiotic carminomycin

Teichoic acid from the cell wall of Actinomadura carminata--a producer of the antibiotic carminomycin

Bioorganicheskaia Khimiia 12(5): 670-678

The cell walls of Actinomadura carminata, producing the antibiotic carminomycin, contain a poly(glycerol phosphate) teichoic acid. The polymer belongs to 1,3-type and consists of about 8 glycerol phosphate units, two of them have 2-acetamido-2-deoxy-alpha-D-galactopyranosyl substituent and one--3-O-methyl-beta-D-galactopyranosyl-(1----3)-2- acetamido-2-deoxy-alpha-D-galactopyranosyl residue at C2 of glycerol. The structure of the polymer was established by chemical analysis and 13C-NMR spectroscopy. The teichoic acid accounted for about 10% of the cell wall dry weight. 3-O-methylgalactose in the structure of the teichoic acid was found for the first time.

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Accession: 041539891

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PMID: 3730009

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