+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

The Hellp syndrome: is this a clinical form of thrombotic microangiopathy?

The Hellp syndrome: is this a clinical form of thrombotic microangiopathy?

Journal de Gynecologie Obstetrique et Biologie de la Reproduction 19(6): 729-736

There are similarities between the clinical, biological and histological features of thrombotic micro-angiopathy (TMA) when it is a complication of pregnancy and the "Help Syndrome" (HS). HS can be associated in pregnancy with pre-eclampsia, thrombocytopenia, micro-angiopathic haemolysis and hepatic cytolysis. We have analysed on the one hand biological features of six cases that occurred in the literature and two personal cases of thrombotic micro-angiopathy that had been proven histologically; and on the other hand the histological findings of the liver in two cases of the literature and in a personal case of HS. Demonstration that in HS deposits exist under the endothelium in the region of the hepatic biopsy suggest that the latter can only be a special clinical form of TMA.

Please choose payment method:

(PDF emailed within 1 workday: $29.90)

Accession: 041559947

Download citation: RISBibTeXText

PMID: 2258593

Related references

Differentiation between severe HELLP syndrome and thrombotic microangiopathy, thrombotic thrombocytopenic purpura and other imitators. European Journal of Obstetrics Gynecology and Reproductive Biology 189: 68-72, 2015

The hellp syndrome is this a clinical form of thrombotic angiopathy. Journal de Gynecologie Obstetrique et biologie de la Reproduction 19(6): 729-736, 1990

HELLP syndrome as a variant of renal thrombotic microangiopathy. Terapevticheskii Arkhiv 75(6): 53-55, 2003

Thrombotic microangiopathy with liver, gut, and bone infarction (catastrophic antiphospholipid syndrome) associated with HELLP syndrome. Clinical Rheumatology 24(2): 166-168, 2005

APS and/or HELLP syndrome Thrombotic microangiopathy with liver, gut, and bone infarction during pregnancy. Journal of Autoimmunity 15(2): A67, 2000

Thrombotic microangiopathy and intravascular hemolysis in pregnancy-induced hypertension. The lie of HELLP syndrome. Cirugia Y Cirujanos 74(3): 211-215, 2006

Thrombotic thrombocytopenic purpura (Moschcowitz syndrome) in a patient with EPH gestosis. The pathophysiologic principle of HELLP syndrome? On the question of the identity of the HELLP syndrome with thrombotic thrombocytopenic purpura. Geburtshilfe und Frauenheilkunde 49(6): 597-600, 1989

De novo thrombotic microangiopathy in renal transplant recipients: a comparison of hemolytic uremic syndrome with localized renal thrombotic microangiopathy. American Journal of Kidney Diseases 41(2): 471-479, 2003

Epidemiology and pathophysiology of adulthood-onset thrombotic microangiopathy with severe ADAMTS13 deficiency (thrombotic thrombocytopenic purpura): a cross-sectional analysis of the French national registry for thrombotic microangiopathy. Lancet. Haematology 3(5): E237-E245, 2016

Thrombotic microangiopathy thrombotic thrombocytopenic purpura and hemolytic uremic syndrome. Orvosi Hetilap 130(33): 1751-1756, 1759, 1989

Thrombotic microangiopathy, hemolytic uremic syndrome, and thrombotic thrombocytopenic purpura. Kidney International 60(3): 831-846, 2001

Thrombotic microangiopathy A proposal for a new terminology for hemolytic uremic syndrome and thrombotic thrombocytopenic purpura. JN Journal of Nephrology 8(1): 3-4, 1995

Ocular thrombotic microangiopathy in atypical hemolytic-uremic syndrome (a clinical case study). Vestnik Oftalmologii 134(5. Vyp. 2): 215-226, 2018

Thrombotic microangiopathy manifesting as thrombotic thrombocytopenic purpura/hemolytic uremic syndrome in the cancer patient. Seminars in Thrombosis and Hemostasis 25(2): 217-221, 1999

Thrombotic microangiopathy in malignant hypertension and hemolytic uremic syndrome (HUS)/ thrombotic thrombocytopenic purpura (TTP): can we differentiate one from the other?. Hypertension Research 28(1): 89-95, 2005