Section 42
Chapter 41,565

The PABA-peptide test: a method in diagnosis of exocrine pancreatic insufficiency

Schneiber, E.; Burgislaus, E.

Medizinische Klinik 74(25): 1000-1003


ISSN/ISBN: 0025-8458
PMID: 314038
Accession: 041564509

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The synthetic peptide N-benzoyl-L-tyrosyl-p-amino-benzoic acid is selectively metabolized by chymotrypsin. Its derivates are excreted in urine and are taken as a measure of exocrine pancreatic insufficiency. The results of PABA-peptide test, of chymotrypsin activity and of the fat content of faeces were compared with each others in 25 patients suspicious to exocrine pancreatic insufficiency. The results correlate well. Because of the practicability the PABA-peptide test is suggested as an additional routine-method in diagnosis of pancreatic functions although it does not substitute any established method.

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