The effect of intramuscular salbutamol in asthmatics
Ingram, J.; Gaddie, J.; Skinner, C.; Palmer, K.N.
British Journal of Clinical Pharmacology 2(3): 263-266
ISSN/ISBN: 0306-5251 PMID: 1234507 DOI: 10.1111/j.1365-2125.1975.tb01585.x
1 In a double-blind placebo controlled dose-response experiment in six asthmatic patients with reversible airways obstruction the effect of i.m. salbutamol (4 mug/kg, 8 mug/kg or 12 mug/kg) was assessed by improvement in spirometry and change in pulse rate. 2 Salbutamol (8 mug/kg) resulted in a mean increase in FEV1 of 1 litre and a mean increase in pulse rate of 7 beats/minute. 3 It was concluded that salbutamol (8 mug/kg) was the optimal dose.