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The effects of the fenoterol hydrobromide (Partusisten) aerosol on uterine activity and the cardiovascular system



The effects of the fenoterol hydrobromide (Partusisten) aerosol on uterine activity and the cardiovascular system



British Journal of Obstetrics and Gynaecology 83(11): 864-869



Fenoterol hydrobromide (Partusisten) aerosol was used in a placebo-controlled, double-blind, double crossover trial to study its effects on oxytocin-induced uterine contractions and the maternal cardiovascular system. The active and placebo aerosols were each administered a total of ten times or twice each in five patients who were in established oxytocin-induced labour with intact membranes. Five puffs, of 200 mug each, of the active aerosol reduced uterine activity by more than half; the effect on the cardiovascular system was to cause a mild tachycardia and to widen the pulse pressure.

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Accession: 041642966

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PMID: 791351


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