The influence of oxygen barotherapy on erythropoiesis in the recuperative period of hemorrhagic collapse
Barkova, E.N.; Petrov, A.V.
Biulleten' Eksperimental'noi Biologii i Meditsiny 81(2): 156-158
ISSN/ISBN: 0365-9615 PMID: 1276404 Accession: 041675903
Under the effect of high-pressure oxygen therapy (2 atm of O2 for 40 min) in anemic rats (blood loss - 2,8% of body weight in the course of 30 min) erythropoiesis in the bone marrow was more intense and led to effective restoration of erythrocytes and hemoglobin in the peripheral blood. Biphasic character of accumulation of erythropoientins in the blood serum of rats was seen on the 1st and the 10th days after acute blood loss. Erythropoiesis inhibitor was revealed in the blood serum of rats on the 15th day. A conclusion was drawn on the importance of erythropoietins and high pressure oxygen therapy in the mechanism of blood regeneration following the loss of blood.