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The luteotrophic effect of estrogen in the rat: prevention by estradiol of the luteolytic effect of an antiserum to luteinizing hormone in the pregnant rat


, : The luteotrophic effect of estrogen in the rat: prevention by estradiol of the luteolytic effect of an antiserum to luteinizing hormone in the pregnant rat. Endocrinology 101(6): 1683-1689

Pregnant rats were injected s.c. with either an antiserum to LH [luteinizing hormone] (LHAS) or with normal horse serum (NHS) on day 10 (day 1: day of insemination), and with either oil or 100 .mu.g of estradiol-17.beta. (E100) on days 9 through 12, 10 through 12, or 11 and 12. Although E100 induced abortion in most rats, the luteolytic effect of the LHAS, as judged by the severity of the fall in the serum progesterone level and the duration of the post-treatment vaginal diestrus, was significantly reduced by E100 treatment on days 9-12, or days 10-12, but not by E100 treatment on days 11 and 12. To see whether another form of estrogen treatment would prevent both LHAS-induced luteolysis and abortion, pregnant rats were given either a cholesterol pellet containing 5 .mu.g of estradiol (E5), or a blank cholesterol pellet, within the bursa of each ovary at 1100 h on day 11, and an s.c. injection of either LHAS or NHS 8 or 12 h later. Abortion occurred before day 15 in 82% of 17 rats in the blank pellet plus LHAS group, in 11% of 18 rats in the E5 plus LHAS group and in none of 9 rats in the E5 plus NHS group. Abortion or the maintenance of pregnancy fitted almost perfectly with the failure or the maintenance of progesterone secretion, respectively. The dependency on LH for the maintenance of progesterone secretion, which appears on day 8 of pregnancy or day 9 of pseudopregnancy, may reflect the role of LH in the regulation of intraluteal estrogen production, since estrogen, at this time, may become an essential part of the luteotrophic process.

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Accession: 041687399

PMID: 590184

DOI: 10.1210/endo-101-6-1683

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Benecke P.; Van Der Ploeg R.R., 1977: Quantification of the temporal relation of the water economy components of a beech and an established pinewood stand in the solling area by soil hydrologic methods. Mueller, Paul (Ed ) Verhandlungen Der Gesellschaft Fuer Oekologie 6 Jahresversammlung Vom 20 Bis 24 September 1976 in Goettingen (Proceedings Of The Ecological Society Sixth Annual Meeting Goettingen, West Germany, Sept 20-24, 1976 ) (In Ger With Engl Summ ) Xv+622p Illus Maps Dr W Junk Bv, Publishers: The Hague, Netherlands Isbn 90-6193-568-7 3-16

Kopecka M., 1977: Biogenesis of the wall fibrillar component in the cell cycle of saccharomyces cerevisiae. Folia Microbiologica 22(6): 440-441

Zhang, Z.; Weintraub, W.S.; Mahoney, E.M.; Spertus, J.A.; Booth, J.; Nugara, F.; Stables, R.H.; Vaccarino, V., 2004: Relative benefit of coronary artery bypass grafting versus stent-assisted percutaneous coronary intervention for angina pectoris and multivessel coronary disease in women versus men (one-year results from the Stent or Surgery trial). Information on the relative benefit of coronary artery bypass grafting (CABG) versus stent-assisted percutaneous coronary intervention (PCI) for improvement of cardiac-related health status in women and how it compares with men is limited. The Ste...

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