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Triacylglycerol biosynthesis in the adipose tissue of the obese-hyperglycaemic mouse

, : Triacylglycerol biosynthesis in the adipose tissue of the obese-hyperglycaemic mouse. Biochemical Journal 158(2): 327-334

Obesity in obese-hyperglycaemic mouse is associated with an increase in number and size of adipocytes. Adipocytes from the obese mouse showed increased incorporation of [14C]acetate and[14C]glucose into triacylglycerol. This increased capacity of triacylglycerol formation was correlated with increased activities of various triacylglycerol-forming enzymes measured in the microsomal fraction of adipose tissue from obese mice. Microsomal fractions from lean and obese mice contained sn-glycerol 3-phosphate acyltransferase, phosphatidate phosphohydrolase and diacylglycerol acyltransferase. Phosphatidate phosphohydrolase was also detected in the soluble fraction. In the presence of Mg2+, the phosphatidate phsophohydrolase from the soluble and the microsomal fractions was active towards membrane-bound phosphatidate. Among the three enzymes studied here, the increase in Mg2+-dependent phosphatidate phosphohydrolase was most prominent in adipose tissue of obese mice.

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Accession: 041864981

PMID: 186034

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Sarmiento, G; Vera, M., 1979: Composition, structure, biomass and primary production of different savannahs in the western plains of Venezuela. Boletin Sociedad Venezolana de Ciencias Naturales 34(136): 5-41

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TRNKA, Z.; MALEK, P.; STERZL, J.; KOLC, J., 1958: Experimental contributions to the lymphatic pathogenesis of anthrax infection. The path of anthrax spores was studied following subcutaneous and intradermal inoculations of sheep. The developed microorganisms appeared 10-16 hours earlier in the lymphatic tissue than in the blood stream.

Nievers, Mirjam G.; Kuikman, Ingrid; Geerts, Dirk, 2000: Formation of hemidesmosome-like structures in the absence of ligand binding by the a6b4 integrin requires binding of HD1/plectin to the cytoplasmic domain of the b4 integrin subunit. Journal of Cell Science 113(6): 3-73

Bae, Jong-Sup; Rezaie, Alireza, R., 2008: Protease activated receptor I PAR-I activation by thrombin is protective in human pulmonary artery endothelial cells if endothelial protein C receptor is occupied by its natural ligand. We recently demonstrated that the occupancy of endothelial protein C receptor (EPCR) by its natural ligand activated protein C (APC)/protein C switches the protease activated receptor I (PAR-I)-dependent signaling specificity of thrombin from a d...

Asthana, Sanjay; Craft, Suzanne; Baker, Laura D.; Raskind, Murray A.; Birnbaum, Roger S.; Lofgreen, Cassin P.; Veith, Richard C.; Plymate, Stephen R., 1999: Cognitive and neuroendocrine response to transdermal estrogen in postmenopausal women with Alzheimer's disease: Results of a placebo-controlled, double-blind, pilot study. Preliminary evidence from clinical studies indicates that treatment with estrogen augments cognitive function for women with Alzheimer's disease (AD). The neurobiology of estrogen, particularly its neuromodulatory and neuroprotective actions,...

Hazarika G.C.; Pandey N.N., 1991: Biochemical profile of goats during experimental chronic hypocalcemia an animal model study. Indian Journal of Animal Sciences 61(1): 67-68

Keeney Dennis; Cruse Richard, 1998: The connection between soil conservation and sustainable agriculture. Pages 185-194 1998

McHugh, S.M.; Roman, S.; Davis, B.; Koch, A.; Pickett, A.M.; Richardson, J.C.; Miller, S.R.; Wetten, S.; Cox, C.J.; Karpe, F.; Todd, J.A.; Bullmore, E.T., 2012: Effects of genetic variation in the P2RX7 gene on pharmacodynamics of a P2X(7) receptor antagonist: a prospective genotyping approach. To investigate the effects of two single nucleotide polymorphisms (SNPs) in the human P2X7 receptor gene (P2RX7) - 168G>A (A348T) and 1513A>C (E496A) - on P2X7 receptor function, using a specific receptor antagonist (GSK137319A) and prospect...

Sasaki S.; Kozlowski T.T., 1968: Effects of herbicides on seed germination and early seedling development of pinus resinosa g. Botanical Gazette 129(3): 238-246