A new method for evaluating acute toxicity intragastrically for classification of chemical substances

Rydzyński, K.; Krysiak, B.

Medycyna Pracy 46(4): 369-383

1995


ISSN/ISBN: 0465-5893
PMID: 7476151
Accession: 042087086

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Abstract
The authors reviewed and presented a critical analysis of the literature on defining acute toxicity of chemicals after intragastrical administration by means of traditional methods and new ones such as fixed procedure, up-down, acute-toxic-classification. Rules and conditions for the evaluation of acute toxicity by means of these methods were presented as well as the way of defining a median, lethal dose administrated intragastrically for the purpose of chemical classification.