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A simple and inexpensive membrane "lung" for small organ perfusion

A simple and inexpensive membrane "lung" for small organ perfusion

Journal of Lipid Research 15(2): 182-186

A disposable coil of thin-walled Silastic tubing, permeable to oxygen and carbon dioxide, functioned as a "lung" for perfusion of isolated rat liver. This "lung," which can be easily assembled from laboratory supplies, has a number of advantages over devices that utilize large air-liquid interfaces for gas exchange. Rates of hepatic lipoprotein triglyceride secretion, comparable to those obtained with more complex oxygenation systems, are achieved with this simple device.

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Accession: 042114471

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PMID: 4832759

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