+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Adrenal sensitivity to adrenocorticotrophin in twin neonates--effect of birth order and growth retardation

Adrenal sensitivity to adrenocorticotrophin in twin neonates--effect of birth order and growth retardation

South African Medical Journal 66(3): 90-92

The sensitivity of the neonatal adrenal gland to injected synthetic adrenocorticotrophin (ACTH) (Synacthen; Ciba-Geigy) 500 micrograms/m2 was assessed in 19 twin pairs by measurement of cortisol and dehydro-epiandrosterone sulphate (DHEAS) before and after injection. Ten of the neonates were growth-retarded with respect to their siblings and 11 pairs were delivered before the onset of labour. The cortisol response to ACTH was not significantly different between labour groups, between the first and second twins or between growth-retarded and non-growth-retarded twins. However, the rise in DHEAS was significantly less in the neonates delivered vaginally after labour. These results suggest that there may be a change in adrenal gland secretion in neonates born after labour compared with those born before the onset of contractions.

Please choose payment method:

(PDF emailed within 1 workday: $29.90)

Accession: 042190484

Download citation: RISBibTeXText

PMID: 6330917

Related references

Contribution of twin pregnancy to perinatal mortality and fetal growth retardation; reversal of growth retardation after birth. Canadian Medical Association Journal 118(4): 365-368, 1978

Effect of intrauterine growth retardation on insulin sensitivity and plasma adiponectin level in neonates. Zhongguo Dang Dai Er Ke Za Zhi 20(8): 618-622, 2018

Effect of maternal betamethasone, birth order, gender and intrauterine growth retardation on the outcome of low birthweight twins. Pediatric Research 41(4 Part 2): 252A, 1997

Effects of birth order, gender, and intrauterine growth retardation on the outcome of very low birth weight in twins. Journal Of Pediatrics. 123(1): 132-136, 1993

Risk of intra-amniotic infection/inflammation and respiratory distress syndrome according to the birth order in twin preterm neonates. Journal of Maternal-Fetal and Neonatal Medicine 2018: 1-6, 2018

The effect of splanchnic nerve section on the sensitivity of the adrenal cortex to adrenocorticotrophin in the calf. Journal of Physiology 390: 23-31, 1987

Twin's Birth-Order Differences in Height and Body Mass Index From Birth to Old Age: A Pooled Study of 26 Twin Cohorts Participating in the CODATwins Project. Twin Research and Human Genetics 19(2): 112-124, 2016

Growth retardation size at birth and perinatal mortality in twin pregnancy. International Journal of Gynecology & Obstetrics 25(5): 399-404, 1987

Condition at birth of a group of neonates suffering from intrauterine growth retardation. Minerva Ginecologica 48(11): 475-479, 1996

A six-months' follow-up study of growth, morbidity and functional immunity in low birth weight neonates with special reference to intrauterine growth retardation in small-for-gestational-age infants. Journal of Tropical Pediatrics 29(5): 278-282, 1983

Intrauterine growth retardation, low birth weight and prematurity in neonates of pregnant women with malaria in Colombia. Revista Da Sociedade Brasileira de Medicina Tropical 44(3): 364-370, 2012

Growth discordance and the effect of a male twin on birth weight of its female co-twin: a population-based study. Journal of Perinatal Medicine 30(6): 510-513, 2002

An Extra-Adrenal Action Of Adrenocorticotrophin: Physiological Induction Of Lipolysis By Secretion Of Adrenocorticotrophin In Obese Rabbits. Journal of Endocrinology 81(3): 281-290, 1979

Personality and birth order in monozygotic twins adopted apart: a test of Sulloway's theory; Research Reviews: twin births and cancer risk in mothers, male sexual dysfunction, twin study of ultimatum game behavior; Human Interest: 'The Land of Twins', twin-like reunion-I, twin-like reunion-II. Twin Research and Human Genetics 11(1): 103-107, 2008

The sensitivity of adrenal responses to synthetic adrenocorticotrophin in the conscious unrestrained calf. Journal of Physiology 245(3): 639-653, 1975