Section 43
Chapter 42,387

Bioavailability of potassium from a slow-release tablet

Ben-Ishay, D.; Engelman, K.

Clinical Pharmacology and Therapeutics 14(2): 250-258


ISSN/ISBN: 0009-9236
PMID: 4695385
DOI: 10.1002/cpt1973142250
Accession: 042386379

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The bioavailability of potassium (K) from orally administered 10 per cent potassium chloride (KCI) solution has been compared with that from a slow-release KCl tablet (Slow-K) in 10 normal subiects under metabolic balance conditions. After a single 40 m Eq. KCl dose, urinary K increased sooner and to greater peak levels after the solution was administered. In both cases greater amounts of K appeared in the urine when administered in the fasting than in the postprandial state.

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