+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

CSF enzymes in lacunar and cortical stroke



CSF enzymes in lacunar and cortical stroke



Stroke 14(2): 266-269



Cerebrospinal fluid enzyme levels of creatine kinase (CK), lactate dehydrogenase (LDH), glutamate oxaloacetate transaminase (GOT) and angiotensin converting enzyme (ACE) were studied in 40 acute stroke patients comprising 20 lacunar strokes and 20 cortical strokes. A marked elevation of at least one of the enzymes CK, GOT or LDH was seen in 80% of cases of cortical strokes. No elevation was seen in lacunar stroke with CK, GOT or ACE and only a slight elevation with LDH. Within the cortical group, there was a correlation between the site, size of infarction seen on CT scan and enzyme level. These findings may help to explain the previously noted unpredictability of rises in CSF enzymes in stroke patients. In certain instances, a study of CSF enzymes may be of use to distinguish cortical from lacunar stroke. A precise diagnosis of lacunar infarction is important for management purposes, entry into stroke treatment trials or description of new syndrome types.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 042429284

Download citation: RISBibTeXText

PMID: 6301113


Related references

Csf enzymes in lacunar and cortical stroke. Stroke 14(2): 266-269, 1983

Blood markers of coagulation, fibrinolysis, endothelial dysfunction and inflammation in lacunar stroke versus non-lacunar stroke and non-stroke: systematic review and meta-analysis. Cerebrovascular Diseases 37(1): 64-75, 2014

Coated-platelets in ischemic stroke: differences between lacunar and cortical stroke. Journal of Thrombosis and Haemostasis 6(4): 609-614, 2008

Lacunar syndromes, small deep infarcts, and final diagnosis of lacunar stroke mechanism The Northern Manhattan Stroke Study. Stroke 28(1): 235, 1997

Family history of stroke is an independent risk factor for lacunar stroke subtype with asymptomatic lacunar infarcts at younger ages. Stroke 42(5): 1196-1200, 2011

Metabolic syndrome relates to lacunar stroke without white matter lesions: a study in first-ever lacunar stroke patients. Cerebrovascular Diseases 29(5): 503-507, 2010

Distinct non-cerebrovascular risk factors for ischemic lacunar stroke and non-lacunar stroke: preliminary results. Genetics and Molecular Research 14(2): 3170-3176, 2016

Apoprotein e phenotype differences in cortical vs lacunar stroke. Neurology 40(4 SUPPL 1): 418, 1990

Coagulation abnormalities in lacunar and cortical ischemic stroke are quite different. Neurological Research 20(1): 15-18, 1998

Plasma lipoproteins and apoproteins in cortical versus lacunar stroke. Neurology 37(3 SUPPL 1): 188, 1987

The electroencephalogram and acute ischemic stroke. Distinguishing cortical from lacunar infarction. Archives of Neurology 45(5): 520-524, 1988

Functional, cognitive and physical outcomes 3 years after minor lacunar or cortical ischaemic stroke. Journal of Neurology, Neurosurgery, and Psychiatry 2018, 2018

Changes in background blood-brain barrier integrity between lacunar and cortical ischemic stroke subtypes. Stroke 39(4): 1327-1332, 2008

Recurrent lacunar infarction following a previous lacunar stroke: a clinical study of 122 patients. Journal of Neurology, Neurosurgery, and Psychiatry 78(12): 1392-1394, 2007

Admission markers predict lacunar and non-lacunar stroke in young patients. Thrombosis Research 128(1): 14-17, 2011