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CSF perfusion to treat intraventricular penicillin toxicity



CSF perfusion to treat intraventricular penicillin toxicity



Archives of Neurology 38(6): 390-391



A shunt infection and meningitis developed in a patient receiving methotrexate intravenously for CNS leukemia. Convulsions and respiratory failure followed the intraventricular administration of 300,000 units of penicillin G potassium. Perfusion with 900 mL of Ringer's lactate removed an amount of penicillin equal to that injected intraventricularly plus some from systemic treatment.

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Accession: 042429339

Download citation: RISBibTeXText

PMID: 7236074

DOI: 10.1001/archneur.1981.00510060092022


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