+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Comparative evaluation of renoscintigraphic properties and plasma clearance of 99MTc-DADS (99mTc-N,N'-bis/mercaptoacetamido ethylenediamine), 99mTc-DTPA and 131I-o-hippuran



Comparative evaluation of renoscintigraphic properties and plasma clearance of 99MTc-DADS (99mTc-N,N'-bis/mercaptoacetamido ethylenediamine), 99mTc-DTPA and 131I-o-hippuran



Nuklearmedizin. Nuclear Medicine 22(3): 136-139



Plasma clearance of 99mTc-N,N'-bis (1,2-mercaptoacetamido) ethylenediamine (DADS), 99mTc-DTPA and 131I-o-hippuran (OIH) was determined in rabbits from blood-concentration decay curves after single i.v. injection of the compounds. Dynamic scintigraphy was performed using the same three compounds, and "activity" curves were compared as observed over kidney ROIs. Both clearance values and renoscintigraphic curves were similar for 99mTc-DADS and 99mTc-DTPA but evidently different from those of OIH. Biliary excretion of 99mTc-DADS was also observed. It appears that, in contrast to other authors, 99mTc-DADS cannot serve as a substitute for 131I-o-hippuran.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 042609780

Download citation: RISBibTeXText

PMID: 6353374


Related references

Advantages of the new radiopharmaceutic agent, 99mTC-mercaptoacetyltriglycine (99mTc-MAG3), in the diagnosis of kidneydiseases. A comparative study with 131I-OIH, 99mTc-DTPA and 99mTc-DMSA. Bratislavske Lekarske Listy 93(5): 258-265, 1992

Clinical evaluation of 99mTc-MAG3 renal imaging: comparison with 99mTc-DTPA, 99mTc-DMSA and 131I-OIH. Kaku Igaku. Japanese Journal of Nuclear Medicine 31(2): 131-142, 1994

99mTc-2,3-diaminopropionic acid complex as renal function agent: comparison of biological properties with 99mTc-DTPA and 131I-OIH. International Journal of Radiation Applications and Instrumentation. Part B Nuclear Medicine and Biology 14(6): 599-604, 1987

Comparative evaluation of 99mTc-pertechnetate, 99mTc-diphosphonate, 99mTc-Solcocitran, 99mTc-iron-ascorbic acid and 67Ga-citrate as brain scanning agents. Nuklearmedizin. Nuclear Medicine 21(6): 265-273, 1982

Study on tumor affinity of technetium-99m-labeled radiopharmaceuticals. (2) 99mTc-Sn-diphosphonate (99mTc-EHDP), 99mTc-Sn-dimercaptosuccinic acid (99mTc-DMSA), and 99mTc-Sn-diethyl stilbestrol diphosphate (99mTc-DSDP). Radioisotopes 25(10): 622-629, 1976

Evaluation of renal function parameters with simultaneously administered 99mTc-DTPA and 131I-hippuran. European Journal of Nuclear Medicine 8(2): 65-71, 1983

Will 99mTc-MAG3 replace 131I-OIH and 99mTc-DTPA in the follow-up of renal transplants?. Contributions to Nephrology 79: 118-122, 1990

99mTc bone scanning agents--VI. Gel chromatographic analysis of the plasma protein binding of 99mTc(Sn)pyrophosphate, 99mTc(Sn)MDP and 99mTc(Sn)HMDP. International Journal of Radiation Applications and Instrumentation. Part B Nuclear Medicine and Biology 15(5): 479-487, 1988

Comparative evaluation of 99mTc GH, 99mTcO4, and 99mTc DTPA as brain imaging agents. Radiology 123(2): 379-383, 1977

Comparison of 99mTc-labelled hepatobiliary agents-- 99mTc-pyridoxylidene glutamate (99mTc-PG) and 99mTc-Sn-lidocaine iminodiacetic acid (99mTc-Sn-LIDA). Nuklearmedizin. Nuclear Medicine 15(6): 290-293, 1976

Scintillation camera renography with 99mTc-DTPA and 131I-Hippuran. Scandinavian Journal of Clinical and Laboratory Investigation 41(2): 189-197, 1981

Renography with a gammacamera. Comparison between 131I-Hippuran and 99mTc-DTPA. Ugeskrift for Laeger 144(37): 2713-2716, 1982

Renal uptakes of 99mTc-MAG3, 99mTc-DTPA, and 99mTc-DMSA in rabbits with unilateral ureteral obstruction. In Vivo 24(2): 137-139, 2010

Complexes 99mTc-Sn-DTPA, 99mTc-Fe-ascorbic acid, and 99mTc-Sn-calcium-gluconogalactogluconate in the diagnosis of renal function and morphology. Polski Przeglad Radiologii i Medycyny Nuklearnej 41(1): 57-61, 1977

Physico-chemical study of the radiopharmaceuticals 99mTc-DMSA, 99mTc-EDTA and 99mTc-DTPA interaction with plasmatic proteins. International Journal of Radiation Applications and Instrumentation. Part A Applied Radiation and Isotopes 40(6): 536-538, 1989