Home
  >  
Section 43
  >  
Chapter 42,619

Comparative use of adenine arabinoside and adenine arabinoside monophosphate in varicella and disseminated zoster in immunosuppressed patients

Vilde, J.L.; Bricaire, F.; Huchon, A.; Brun-Vezinet, F.

Journal of Medical Virology 12(2): 149-153

1983

ISSN/ISBN: 0146-6615
PMID: 6194253
DOI: 10.1002/jmv.1890120209
Accession: 042618202
Download citation:  
Text
  |  
BibTeX
  |  
RIS
Adenine arabinoside monophosphate (ARA AMP) was used in ten immunosuppressed patients suffering from varicella or disseminated zoster, and compared to adenine arabinoside (vidarabine) in ten other similar patients. Good results were obtained with both drugs: the fever stopped suddenly in three or four days and no new vesicles were observed after the third day. ARA AMP is more soluble than vidarabine and is thus easier to handle; it could be an effective treatment of severe varicella-zoster virus infections in immunosuppressed patients.

Comparative use of adenine arabinoside and adenine arabinoside monophosphate in varicella and disseminated zoster in immunosuppressed patients

Full Text Article emailed within 0-6 h: $19.90




Related References

Soike, K.F.; Felsenfeld, A.D.; Gibson, S.; Gerone, P.J. 1980: Ineffectiveness of adenine arabinoside and adenine arabinoside 5'-monophosphate in simian varicella infection Antimicrobial Agents and ChemoTherapy 18(1): 142-147
Perrillo, R.P.; Regenstein, F.G.; Bodicky, C.J.; Campbell, C.R.; Sanders, G.E.; Sunwoo, Y.C. 1985: Comparative efficacy of adenine arabinoside 5' monophosphate and prednisone withdrawal followed by adenine arabinoside 5' monophosphate in the treatment of chronic active hepatitis type B Gastroenterology (New York, Ny 1943) 88(3): 780-786
Perrillo, R.P.; Regenstein, F.G.; Bodicky, C.J.; Campbell, C.R.; Sanders, G.E.; Sunwoo, Y.C. 1985: Comparative efficacy of adenine arabinoside 5' monophosphate and prednisone withdrawal followed by adenine arabinoside 5' monophosphate in the treatment of chronic active hepatitis type B Gastroenterology 88(3): 780-786
Bryson, Y.J.; Kronenberg, L.H. 1977: Combined antiviral effects of interferon, adenine, arabinoside, hypoxanthine arabinoside, and adenine arabinoside-5'-monophosphate in human fibroblast cultures Antimicrobial Agents and ChemoTherapy 11(2): 299-306
Vildé, J.L.; Bricaire, F.; Huchon, A.; Dournon, E.; Brun-Vezinet, F.; Leport, C.; Bastin, R. 1982: Adenine arabinoside treatment of varicella and generalized herpes zoster in 43 immunosuppressed patients La Nouvelle Presse Medicale 11(48): 3547-3550
Bryson, Y.J.; Connor, J.D. 1976: In vitro susceptibility of varicella zoster virus to adenine arabinoside and hypoxanthine arabinoside Antimicrobial Agents and ChemoTherapy 9(3): 540-543
Kern, E.R.; Richards, J.T.; Overall, J.C.; Glasgow, L.A. 1977: Genital Herpesvirus homonis infection in mice. II. Treatment with phosphonoacetic acid, adenine arabinoside, and adenine arabinoside 5'-monophosphate Journal of Infectious Diseases 135(4): 557-567
Klein, R.J.; Friedman-Kien, A.E. 1977: Latent herpes simplex virus infections in sensory ganglia of mice after topical treatment with adenine arabinoside and adenine arabinoside monophosphate Antimicrobial Agents and ChemoTherapy 12(5): 577-581
Kern, E.R.; Richards, J.T.; Overall, J.C.; Glasgow, L.A. 1978: Alteration of mortality and pathogenesis of three experimental Herpesvirus hominis infections of mice with adenine arabinoside 5'-monophosphate, adenine arabinoside, and phosphonoacetic acid Antimicrobial Agents and ChemoTherapy 13(1): 53-60
Hoofnagle, J.H. 1986: Therapy of chronic type B hepatitis with adenine arabinoside and adenine arabinoside monophosphate Journal of Hepatology 3(Suppl 2): S73-S80
Sauer, O.; Werner, G.T.; Schneider, H.; Lenard, H.G.; von Haselberg, L.; Nettesheim, H.J. 1979: Preliminary clinical experiences with adenine arabinoside monophosphate (ARA-AMP) in encephalitis due to viruses of the herpes group and varicella/zoster infections Klinische Padiatrie 191(6): 566-571
Sauer, O.; Huth, E.; Lenard, H.G.; Schneider, H.; von Haselberg, L.; Nettesheim, H.J.; Werner, G.T. 1980: Preliminary animal experimental results and clinical experiences with the antiviral agent adenine arabinoside monophosphate in encephalitis from herpes group and varicella-zoster infections Monatsschrift für Kinderheilkunde 128(5): 248-250
Mikulec, D. 1975: Sensitivities of herpes simplex virus type 1 and type 2 and varicella zoster virus to adenine arabinoside and hypo xanthine arabinoside Pavan Langston, Deborah, Robert Anan And Charles A. Alford, Jr. (ed.). Adenine Arabinoside: An Antiviral Agent. Symposium San Francisco, Calif., U.s.a. Sept. 16-17, . Xviii 425p. Illus. Raven Press, Publishers: New York, N.y., U.s.a. ISBN 0-89004-024-9: 171-175
Johnson, M.T.; Buchanan, R.A.; Luby, J.P.; Mikulec, D. 1975: Treatment of varicella-zoster virus infections with adenine arabinoside Journal of Infectious Diseases 131(3): 225-229
Whitley, R.J.; Ch'ien, L.T.; Dolin, R.; Galasso, G.J.; Alford, C.A. 1976: Adenine arabinoside therapy of herpes zoster in the immunosuppressed. NIAID collaborative antiviral study New England Journal of Medicine 294(22): 1193-1199
Falcon, M.G.; Jones, B.R. 1977: Antiviral activity in the rabbit cornea of adenine arabinoside, Ara-A 5' monophosphate, and hypoxanthine arabinoside; and interactions with adenosine deaminase inhibitor Journal of General Virology 36(1): 199-202
Feldman, S.; Roberson, P.K.; Lott, L.; Thornton, D. 1986: Neurotoxicity complicating adenine arabinoside therapy for varicella and herpes zoster infection Pediatric Research 20(4 Part 2): 309A
Koszalka, G.W.; Averett, D.R.; Fyfe, J.A.; Roberts, G.B.; Spector, T.; Biron, K.; Krenitsky, T.A. 1991: 6-N-substituted derivatives of adenine arabinoside as selective inhibitors of varicella-zoster virus Antimicrobial Agents and ChemoTherapy 35(7): 1437-1443
Ch'ien, L.T.; Whitley, R.J.; Alford, C.A.; Galasso, G.J. 1976: Adenine arabinoside for therapy of herpes zoster in immunosuppressed patients: preliminary results of a collaborative study Journal of Infectious Diseases 133 Suppl: A184-A191
Gephart, J.F.; Lerner, A.M. 1979: In vitro susceptibility to human herpesviruses and cellular toxicity of adenine arabinoside adenine arabinoside mono phosphate and arabinosyl hypo xanthine Clinical Research 27(4): 696A