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Comprehensive study of haemostasis in chronic uraemia



Comprehensive study of haemostasis in chronic uraemia



Nephron 33(1): 5-8



A comprehensive study of haemostasis has been performed in a homogeneous group of 25 adult patients with conservatively treated chronic uraemia. We have found prolonged bleeding time, impaired platelet adhesiveness and aggregation, and decreased platelet factor 3 activity, increased values of fibrinogen, of factor VIII activity and related antigen, and of combined levels of factors II, VII and X. Non-significantly abnormal concentrations of factor XIII and of plasminogen and significantly lower values of plasminogen activators and higher values of urokinase inhibitors and anti-plasmin have also been found. Fibrinogen degradation products were detected in the urine of some patients.

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Accession: 042637781

Download citation: RISBibTeXText

PMID: 6403879

DOI: 10.1159/000182894


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