+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Detection of antibodies to human coronaviruses 229E and OC43 in the sera of multiple sclerosis patients and normal subjects



Detection of antibodies to human coronaviruses 229E and OC43 in the sera of multiple sclerosis patients and normal subjects



Infection and Immunity 41(1): 426-429



Sera collected from 90 multiple sclerosis patients and 148 age-matched normal subjects were examined for the presence of antibodies against human coronaviruses (HCV) 229E and OC43 by enzyme immunoassay (EIA). The results demonstrated no significant difference between the MS patients and the normal subjects in their antibody titer to HCV 229E and HCV OC43. Further analysis of these 238 sera indicated that a stronger EIA reaction was generally observed against HCV OC43 (mean EIA value at an optical density of 492 nm = 0.896) than against HCV 229E (mean EIA value at an optical density of 492 nm = 0.346).

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 042767364

Download citation: RISBibTeXText

PMID: 6345398


Related references

Antibodies to coronaviruses OC43 and 229E in multiple sclerosis patients. Neurology 32(3): 292-295, 1982

Comparison of immunofluorescence with monoclonal antibodies and RT-PCR for the detection of human coronaviruses 229E and OC43 in cell culture. Journal Of Virological Methods. 72(2): 145-152, E, 1998

Coronavirus isolates SK and SD from multiple sclerosis patients are serologically related to murine coronaviruses A59 and JHM and human coronavirus OC43, but not to human coronavirus 229E. Journal of Virology 38(1): 231-238, 1981

Antibodies to human coronaviruses 229E and OC43 in the population of C.R. Acta Virologica 34(4): 346-352, 1990

Antigenicity analysis of nucleocapsid proteins of 3 human coronaviruses SARS-CoV, 229E and OC43 with their monoclonal antibodies. Nan Fang Yi Ke Da Xue Xue Bao 26(3): 290-293, 2006

Evaluation of nested polymerase chain methods for the detection of human coronaviruses 229E and OC43. Molecular and Cellular Probes 8(5): 357-364, 1994

Production of specific antibodies against SARS-coronavirus nucleocapsid protein without cross reactivity with human coronaviruses 229E and OC43. Journal of Veterinary Science 11(2): 165-167, 2010

Immunogenicity and antigenicity of human coronaviruses 229E and OC43. Infection and Immunity 32(3): 1000-1006, 1981

Prevalence of Antibody to Human Coronaviruses 229E, Oc43 and Neonatal Calf Diarrhea Coronavirus (Ncdcv) in Patients of Northern Italy. European Journal of Epidemiology 2(2): 112-117, 1986

Prevalence of antibody to human coronaviruses 229E, OC43 and neonatal calf diarrhea coronavirus (NCDCV) in patients of Northern Italy. European Journal of Epidemiology 2(2): 112-117, 1986

Studies with human coronaviruses. II. Some properties of strains 229E and OC43. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine 139(3): 722-727, 1972

Polypeptides and functions of antigens from human coronaviruses 229E and OC43. Infection and Immunity 35(2): 515-522, 1982

Serological responses in patients with severe acute respiratory syndrome coronavirus infection and cross-reactivity with human coronaviruses 229E, OC43, and NL63. Clinical and Diagnostic Laboratory Immunology 12(11): 1317-1321, 2005

Direct diagnosis of human respiratory coronaviruses 229E and OC43 by the polymerase chain reaction. Journal of Virological Methods 97(1/2): 59-66, 2001

Clinical impact of human coronaviruses 229E and OC43 infection in diverse adult populations. Journal of Infectious Diseases 208(10): 1634-1642, 2013