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Diagnostic specificity of serum myoglobin radioimmunoassay for acute myocardial infarction is improved by using age-, sex-, and race-specific reference ranges


, : Diagnostic specificity of serum myoglobin radioimmunoassay for acute myocardial infarction is improved by using age-, sex-, and race-specific reference ranges. Clinical Chemistry 28(10): 2179-2179


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Maxon H.R.; Chen I.W.; Gerson M.; Sperling M.; Stein E., 1981: Improved diagnostic specificity of serum myo globin radio immunoassay for acute myo cardial infarction using age adjusted sex adjusted and race adjusted reference ranges. Journal of Nuclear Medicine 22(6): P45

Reese, L.; Uksik, P., 1981: Radioimmunoassay of serum myoglobin in screening for acute myocardial infarction. Over an 8-month period 289 patients consecutively admitted to a coronary care unit were studied to assess the value of serum myoglobin determinations by radioimmunoassay in screening for acute myocardial infarction. Of the 289 patients 127 (44%) h...

Stone, M.J.; Willerson, J.T.; Gomez-Sanchez, C.E.; Waterman, M.R., 1975: Radioimmunoassay of myoglobin in human serum. Results in patients with acute myocardial infarction. A radioimmunoassay has been developed for the measurement of serum myoglobin in order to evaluate the time-course and frequency of myoglobinemia in patients with acute myocardial infarction. The method can detect as little as 0.5 ng of myoglobin a...

Lin, J.H., 1981: Radioimmunoassay of serum myoglobin and its preliminary clinical application on the early diagnosis of acute myocardial infarction. Zhonghua Xin Xue Guan Bing Za Zhi 9(4): 296-298

Kubasik, N.P.; Guiney, W.; Warren, K.; D'Souza, J.P.; Sine, H.E.; Brody, B.B., 1978: Radioimmunoassay of serum myoglobin: evaluation and modification of a commercial kit and assessment of its usefulness for detecting acute myocardial infarction. We evaluated a modified procedure for a commercially available myoglobin radioimmunoassay kit (Nuclear Medical Systems). Within-run and run-to-run precision was acceptable. Normal ranges were established and paralelism studies performed. Clinical...

D'Annunzio, E.; Mobilij, A.; D'Orazio, G.; Volpi, G.; Paloscia, L.; Rasetti, G.; Pontano, O.; Sclocco, T., 1981: Evaluation of the therapeutic action of D-L carnitine in acute myocardial infarct (AMI) by changes in the serum myoglobin concentration curve. I. Myoglobin: earliest serum test of necrosis in the acute phase of myocardial infarction. Bollettino Della Societa Italiana di Cardiologia 26(11): 1447-1451

Venge, P., 1983: The diagnostic and prognostic value of serum-myoglobin determinations in acute myocardial infarction. Upsala Journal of Medical Sciences 88(3): 205-211

Brogan, G.X.Jr; Vuori, J.; Friedman, S.; Mccuskey, C.F.; ThodeHenry C.Jr.; Vaananen, H.K.lervo; Cooling, D.S.; Bock, J.L., 1996: Improved specificity of myoglobin plus carbonic anhydrase assay versus that of creatine kinase-MB for early diagnosis of acute myocardial infarction. Study objective: Carbonic anhydrase III (CA-III) is an enzyme released from skeletal muscle in a fixed ratio with myoglobin during cell injury, but unlike myoglobin it is not found in cardiac muscle. This study compared the clinical utility of ser...

Brogan, G.X.; Vuori, J.; Friedman, S.; McCuskey, C.F.; Thode, H.C.; Vaananen, H.K.; Cooling, D.S.; Bock, J.L., 1996: Improved specificity of myoglobin plus carbonic anhydrase assay versus that of creatine kinase-MB for early diagnosis of acute myocardial infarction. Carbonic anhydrase III (CA-III) is an enzyme released from skeletal muscle in a fixed ratio with myoglobin during cell injury, but unlike myoglobin it is not found in cardiac muscle. This study compared the clinical utility of serum myoglobin (S-M...

Stone, M.J.; Waterman, M.R.; Harimoto, D.; Murray, G.; Willson, N.; Platt, M.R.; Blomqvist, G.; Willerson, J.T., 1977: Serum myoglobin level as diagnostic test in patients with acute myocardial infarction. Serum myoglobin levels were measured in normal subjects and patients by means of a newly developed radioimmunoassay. Myoglobin was identified in all of 135 sera from normal adults and ranged between 6 and 85 ng/ml (mean +/- SE 31 +/- 1.3). Raised...