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Differentiating atopic patients by means of alpha 1-antitrypsin phenotypes

Differentiating atopic patients by means of alpha 1-antitrypsin phenotypes

Allergologia et Immunopathologia 12(2): 111-114

We have divided ninety three patients in two groups, accordingly to their symptomatology. After getting each patient Alpha 1 Antitrypsin phenotype by means of Isoelectrofocusing with polyacrylamyde plates (pH 4-5), it was verified that the group without Atopic Dermatitis had more MS phenotypes in statistically significant quantities (p less than 0.005) and those with Atopic Dermatitis showed more variety of MZ phenotypes (p less than 0,025). That is why we outline that, thanks to individual conditionings a single pathogenic mechanism may preferently take place in each case leading us to conclude that the Atopy may be considered as a Syndrome more than an illness.

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Accession: 042818387

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PMID: 6331763

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