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Effect of leprosy sera and foetal calf serum (FCS) on the T cell number of peripheral blood of leprosy patients



Effect of leprosy sera and foetal calf serum (FCS) on the T cell number of peripheral blood of leprosy patients



Indian Journal of Leprosy 56(4): 784-791



Study was conducted in 24 cases of various types of leprosy and 10 healthy controls to find out the effect of various sera on the T cell count of peripheral blood lymphocytes by sheep erythrocyte rosetting method. The percentage of T lymphocytes in lepromatous and tuberculoid cases were significantly lower compared to that in normal healthy controls. All sera except FCS had a stimulatory effect on the number of T cells. The cells incubated for 24 hours in FCS did not show any stimulatory effect on the number of T cells, however, these FCS incubated cells showed a significant elevation in the number of T cells when further incubated in sera either from leprosy cases or from healthy subjects.

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Accession: 042915870

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PMID: 6335891


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