+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Effects of nasal continuous positive airway pressure on lung function in patients with sleep obstructive apnea syndrome



Effects of nasal continuous positive airway pressure on lung function in patients with sleep obstructive apnea syndrome



Archivos de Bronconeumologia 31(1): 18-22



Sixty-one patients with obstructive sleep apnea syndrome (OSAS), 26 of whom also had chronic obstructive pulmonary disease (COPD), received treatment by nasal continuous positive airways pressure (nCPAP). To evaluate the effects of this device on daytime lung function, we analyzed pulmonary function tests before treatment with nCPAP and after a mean follow-up period of 12 months (range: 2-22 months). In patients with both OSAS and COPD, we observed a significant decrease in PaCO2 (p < 0.007), in airways resistance (p < 0.002) and in residual volume (p < 0.01); for these same patients we recorded increases in forced vital capacity (p < 0.04) and maximum inspiratory pressure (p < 0.02). We saw no change in lung function in patients with OSAS only. PaO2 increased after treatment in the 15 patients who were initially hypoxemic (p < 0.001). We conclude that after treatment with nCPAP, the greatest changes in respiratory function occur in patients with both OSAS and COPD, who also experience slight decrease in body weight. These changes may be explained by a decrease in auto-PEEP and weight loss.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 042960283

Download citation: RISBibTeXText

PMID: 7881710


Related references

Effects of long-term nasal continuous positive airway pressure therapy on morphology, function, and mucociliary clearance of nasal epithelium in patients with obstructive sleep apnea syndrome. Laryngoscope 114(8): 1431-1434, 2004

Long-term effects of nasal continuous positive airway pressure on pulmonary function and blood gas data in patients with obstructive sleep apnea syndrome. Nihon Kokyuki Gakkai Zasshi 36(12): 1011-1016, 1998

Long-term effects of treatment with nasal continuous positive airway pressure on daytime lung function and pulmonary hemodynamics in patients with obstructive sleep apnea. American Review of Respiratory Disease 141(4 Pt 1): 866-870, 1990

Effects of nasal continuous positive airway pressure on patients with obstructive sleep apnea syndrome. Journal of the Formosan Medical Association 90(3): 296-299, 1991

Long term lung function changes in patients with obstructive sleep apnea during treatment with nasal continuous positive airway pressure. Thorax 42(9): 722, 1987

The immediate effects of nasal continuous positive airway pressure treatment on sleep pattern in patients with obstructive sleep apnea syndrome. Electroencephalography & Clinical Neurophysiology 63(1): 10-17, 1986

Renal function in patients with obstructive sleep apnea. Effects of nasal continuous positive airway pressure. Archives of Internal Medicine 148(6): 1337-1340, 1988

Long-term effects of nasal continuous positive airway pressure on vasodilatory endothelial function in obstructive sleep apnea syndrome. Sleep and Breathing 9(3): 97, 2005

Obstructive sleep apnea syndrome affects left ventricular diastolic function: effects of nasal continuous positive airway pressure in men. Circulation 112(3): 375-383, 2005

Obstructive Sleep Apnea Syndrome Affects Left Ventricular Diastolic Function: Effects of Nasal Continuous Positive Airway Pressure in Men. Yearbook of Pulmonary Disease 2007: 252-253, 2007

Effects of nasal continuous positive airway pressure (NCPAP) on nocturnal renal function in obstructive sleep apnea syndrome (OSAS). Nihon Kyobu Shikkan Gakkai Zasshi 29(5): 573-577, 1991

Effects of nasal continuous positive airway pressure therapy on respiratory parameters of upper airway patency in patients with obstructive sleep apnea syndrome. Chest 114(3): 691-696, 1998

Platelet activation in patients with obstructive sleep apnea syndrome and effects of nasal-continuous positive airway pressure. Tokai Journal of Experimental and Clinical Medicine 27(4): 107-112, 2002

Blood viscosity and platelet function in patients with obstructive sleep apnea syndrome treated with nasal continuous positive airway pressure. Clinical Hemorheology and Microcirculation 27(3-4): 201-207, 2002

Effects of long term nasal continuous positive airway pressure on the blood pressure of patients with obstructive sleep apnea hypopnea syndrome. Zhonghua Jie he He Hu Xi Za Zhi 35(9): 687-690, 2012