+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Experimental reconstruction of mandibular defects with vascularized iliac bone grafts



Experimental reconstruction of mandibular defects with vascularized iliac bone grafts



Journal of Oral and Maxillofacial Surgery 53(5): 566-571



The study evaluated the processes of incorporation and bone remodeling after microsurgical transplantation of iliac crest grafts for mandibular defect reconstruction. A defect in the mandibular angle measuring 2 x 4 x 1 cm was reconstructed in six Göttingen minipigs with a microvascularized iliac bone graft based on the circumflex artery. The animals were killed at 14, 28, and 56 days after transplantation and the healing process was histologically examined. Although a constant vascular supply to the graft was restored by the microvascular reanastomosis, necrosis occurred in the major part of the bone marrow. New bone formation from the graft was markedly delayed compared with that from the mandible. Some osteocytes and marrow survived after grafting, but the volume of iliac bone tended to decrease gradually over time. In the 56-day specimens, the border between the graft and the mandible was not clear. These findings indicate that survival of the vascularized iliac bone graft in the minipig is not complete.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 043083868

Download citation: RISBibTeXText

PMID: 7722726

DOI: 10.1016/0278-2391(95)90070-5


Related references

Mandibular reconstruction using vascularized iliac bone grafts. Plastic Surgical Nursing 7(4): 128, 1987

Evaluation of postoperative changes in vascularized iliac bone grafts used for mandibular reconstruction. International Journal of Oral and Maxillofacial Surgery 47(8): 990-997, 2018

Experimental transplantation of vascularized autologous and allogenic bone grafts for mandibular defects anatomical immunological and surgical basis for vascularized bone transfer in the goettingen minipig. International Journal of Oral & Maxillofacial Surgery 20(4): 239-244, 1991

Influence of the prosthetic restoration modality on bone loss around dental implants placed in vascularized iliac bone grafts for mandibular reconstruction. Otolaryngology--Head and Neck Surgery 123(5): 598-602, 2000

Analysis of reconstruction using non-vascularized iliac bone graft for patients with mandibular defects. Hua Xi Kou Qiang Yi Xue Za Zhi 30(4): 411-413, 2012

Immediate vascularized bone reconstruction of anterior mandibular defects with free iliac crest. Laryngoscope 101(7 Pt 1): 791-794, 1991

Experimental study on the comparison of iliac and mandibular grafts in the reconstruction of mandibular defects. Zhonghua Kou Qiang Yi Xue Za Zhi 23(1): 43-45, 1988

A comparison of vascularized and nonvascularized bone grafts for reconstruction of mandibular continuity defects. Journal of Oral and Maxillofacial Surgery 55(11): 1200-1206, 1997

ITI dental implants immediately placed into vascularized iliac bone grafts for reconstruction of mandibular defect: analysis of 12 consecutive cases. Shanghai Kou Qiang Yi Xue 14(2): 103-107, 2005

Efficacy of PRP in the Reconstruction of Mandibular Segmental Defects Using Iliac Bone Grafts. Journal of Maxillofacial and Oral Surgery 12(2): 160-167, 2013

Immediate reconstruction of mandibular defects with revascularized iliac bone grafts after radical surgery for osteosarcoma. Proceedings of the Finnish Dental Society. Suomen Hammaslaakariseuran Toimituksia 86(3-4): 149-155, 1990

Computer-assisted Secondary Reconstruction of Mandibular Continuity Defects Using Non-Vascularized Iliac Crest Bone Graft Following Oral Cancer Resection. Journal of Hard Tissue Biology 26(4): 386-392, 2017

Application of individual prefabricated reconstructive titanic plate combined with vascularized iliac bone-muscular flap for reconstruction of mandibular defects. Zhonghua Zheng Xing Wai Ke Za Zhi 32(4): 258-263, 2016

Reconstruction of mandibular defects with composite autologous iliac bone and freeze-treated allogeneic rib grafts. Journal of Oral and Maxillofacial Surgery 40(1): 29-33, 1982

Mandibular reconstruction using free vascularized iliac crest grafts and dental implants. Clujul Medical 88(3): 391-394, 2015