Section 44
Chapter 43,184

Gene encoding the collagen type I and thrombospondin receptor CD36 is located on chromosome 7q11.2

Fernández-Ruiz, E.; Armesilla, A.L.; Sánchez-Madrid, F.; Vega, M.A.

Genomics 17(3): 759-761


ISSN/ISBN: 0888-7543
PMID: 7503937
DOI: 10.1006/geno.1993.1401
Accession: 043183027

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The human CD36 is a member of a gene family of structurally related glycoproteins and functions as a receptor for collagen type I and thrombospondin. CD36 also binds to red blood cells infected with the human malaria parasite Plasmodium falciparum. In the present study, the CD36 gene was assigned to chromosome 7 by using the polymerase chain reaction with DNA from human-hamster somatic cell hybrids. Furthermore, the use of a CD36 genomic probe has allowed the localization of the CD36 locus to the 7q11.2 band by fluorescence in situ hybridization coupled with GTG-banding.

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