EurekaMag
+ Most Popular
Cunninghamia lanceolata plantations in China
Mammalian lairs in paleo ecological studies and palynology
Studies on technological possibilities in utilization of anhydrous milk fat for production of recombined butter-like products
Should right-sided fibroelastomas be operated upon?
Large esophageal lipoma
Apoptosis in the mammalian thymus during normal histogenesis and under various in vitro and in vivo experimental conditions
Poissons characoides nouveaux ou non signales de l'Ilha do Bananal, Bresil
Desensitizing efficacy of Colgate Sensitive Maximum Strength and Fresh Mint Sensodyne dentifrices
Administration of fluid by subcutaneous infusion: revival of a forgotten method
Tundra mosquito control - an impossible dream?
Schizophrenia for primary care providers: how to contribute to the care of a vulnerable patient population
Geochemical pattern analysis; method of describing the Southeastern limestone regional aquifer system
Incidence of low birth weights in a hospital of Mexico City
Tabanidae
Graded management intensity of grassland systems for enhancing floristic diversity
Microbiology and biochemistry of cheese and fermented milk
The ember tetra: a new pygmy characid tetra from the Rio das Mortes, Brazil, Hyphessobrycon amandae sp. n. (Pisces, Characoidei)
Risk factors of contrast-induced nephropathy in patients after coronary artery intervention
Renovation of onsite domestic wastewater in a poorly drained soil
Observations of the propagation velocity and formation mechanism of burst fractures caused by gunshot
Systolic blood pressure in a population of infants in the first year of life: the Brompton study
Haematological studies in rats fed with metanil yellow
Studies on pasteurellosis. I. A new species of Pasteurella encountered in chronic fowl cholera
Dormancy breaking and germination of Acacia salicina Lindl. seeds
therapy of lupus nephritis. a two-year prospective study

Humoral and cellular immune response to varicella-zoster virus in children inoculated with live attenuated varicella vaccine


Humoral and cellular immune response to varicella-zoster virus in children inoculated with live attenuated varicella vaccine



Biken Journal 23(3): 135-141



ISSN/ISBN: 0006-2324

PMID: 6257227

Twenty-seven hospitalized children without a history of varicella were vaccinated with 500 plaque forming units of live attenuated varicella vaccine (Oka strain) and followed for four to five weeks at weekly intervals for the development of virus-specific cell-mediated immunity (CMI) and neutralizing (NT) antibody activity. These children had suffered from heterogeneous underlying diseases, such as acute leukemia, lymphoma, the nephrotic syndrome, and other chronic illnesses and were in various immunological states. Development of specific CMI, detected by lymphocyte transformation (LTF), was observed in 23 of the 27 children. The appearance of LTF activity in immunologically handicapped patients was delayed and/or rather suppressed compared with that of immunologically normal patients. An antibody response was detected in 26 of the 27 children. All of the vaccinated patients were protected effectively against a subsequent outbreak of varicella in the ward.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 043293347

Download citation: RISBibTeXText

Related references

Live attenuated varicella vaccine: evidence that the virus is attenuated and the importance of skin lesions in transmission of varicella-zoster virus. National Institute of Allergy and Infectious Diseases Varicella Vaccine Collaborative Study Group. Journal of Pediatrics 116(2): 184-189, 1990

Association between antibody response to live attenuated varicella zoster virus vaccine and subsequent varicella-like illness in Canadian children immunized during the second year of life. Pediatric Research 37(4 Part 2): 110A, 1994

Varicella zoster virus infections in children after the introduction of live attenuated varicella vaccine. Current Opinion in Pediatrics 16(1): 80-84, 2004

Varicella-Zoster Virus-Specific Cellular Immune Responses to the Live Attenuated Zoster Vaccine in Young and Older Adults. Journal of Immunology 199(2): 604-612, 2017

Age-related differences in cell-mediated immunity to varicella-zoster virus among children and adults immunized with live attenuated varicella vaccine. Journal of Infectious Diseases 171(1): 13-17, 1995

A phase I-II study of live attenuated varicella-zoster virus vaccine to boost immunity in human immunodeficiency virus-infected children with previous varicella. Pediatric Infectious Disease Journal 28(7): 653-655, 2009

Expression of interleukin-2 receptor, CD25, on CD4 lymphocytes in response to varicella-zoster virus antigen among patients with malignancies immunized with live attenuated varicella vaccine. Pediatrics International: Official Journal of the Japan Pediatric Society 41(1): 32-36, 1999

High Constitutive Interleukin 10 Level Interferes With the Immune Response to Varicella-Zoster Virus in Elderly Recipients of Live Attenuated Zoster Vaccine. Journal of Infectious Diseases 219(8): 1338-1346, 2019

Protective efficacy of live attenuated varicella zoster virus vaccine against naturally acquired varicella zoster infection. Pediatric Research 16(4 Part 2): 148A, 1982

Live attenuated varicella vaccine: Evidence that the virus is attenuated and the importance of skin lesions in transmission of varicella-zoster virus. The Journal of Pediatrics 116(2): 184-189, 1990

T lymphocyte cytotoxicity with natural varicella-zoster virus infection and after immunization with live attenuated varicella vaccine. Journal of Immunology 142(2): 636-641, 1989

T lymphocyte cytotoxicity with natural varicella-zoster virus infection and after immunization with live attenuated varicella vaccine. The Journal of Immunology (1950) 142(2): 636-641, 1989

Cellular and humoral immune responses to varicella-zoster virus in immunocompromised patients during and after varicella-zoster infections. Infection and Immunity 25(1): 170-174, 1979

Live Attenuated Zoster Vaccine Boosts Varicella Zoster Virus (VZV)-Specific Humoral Responses Systemically and at the Cervicovaginal Mucosa of Kenyan VZV-Seropositive Women. Journal of Infectious Diseases 218(8): 1210-1218, 2018

Responses of varicella zoster virus (VZV)-specific immunity in seropositive adults after inhalation of inactivated or live attenuated varicella vaccine. Vaccine 20(31-32): 3638-3643, 2002