+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Mucoceles of the minor salivary glands. Extravasation mucoceles (mucus granulomas) and retention mucoceles (mucus retention cysts)



Mucoceles of the minor salivary glands. Extravasation mucoceles (mucus granulomas) and retention mucoceles (mucus retention cysts)



Hno 29(6): 179-191



360 cases of salivary glands cysts (= 6%) were collected in the Salivary Glands Register (Institute of Pathology, University of Hamburg) from 1965 until 1979 among a total of 5739 register cases. 273 cases of the cystic lesions (= 76%) were mucoceles of the minor salivary glands. The analysis of these 273 cases revealed the following results: 1. Two types of mucoceles can be morphologically distinguished: extravasation mucoceles and retention mucoceles. 2. The extravasation mucocele is in our material (240 cases = 88.7%) the most frequent type of mucocele. The term "extravasation mucocele" of the anglo-american literature is identical with the term "mucus granuloma" ("Schleimgranulom") introduced by Hamperl (1932). 3. The main signs of the mucus granulomas are: predominant location (79%) at the lower lip, age peak in the 2nd decade and more frequent occurrence (in 60%) in the male sex. 4. Three stages of development can be distinguished in the pathogenesis of the mucus granulomas: an initial stage (interstitial mucus lakes), a resorption stage (mucus granulomas with macrophages, foam cells and foreign bodies giant cells) and a terminal stage with the development of a pseudocyst (capsule of collagen tissue, no epithelial demarcation). 5. The retention mucocele (synonym: mucus retention cyst) is a rare type of mucocele (33 cases = 11.3%). The main signs are: nearly equal occurrence in all oral regions, age peak in the 8th decade, moderate predominance of the female sex. 6. The retention mucoceles contain viscous mucous material, possess always an epithelial demarcation of the cysts differentiated analogous to the different segments of the salivary duct system and show as a rule no inflammatory reaction compared with the extravasation mucoceles. 7. Microtraumas and mucus congestions play the important role in the development of the extravasation mucocele. The final formation depends on the amount of the overflowed mucus and the intensity of the mucus phagocytosis. 8. Partial obstructions of the ducts are considered as the important factor in the development of the retention mucocele. Besides, relations are discussed to high differentiated monomorphic adenomas. 9. In differential diagnosis, the retention mucoceles must be distinguished from other salivary glands cysts (lymphoepithelial cysts etc.), the extravasation mucoceles from other granulomatous reactions of the salivary glands.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 043692842

Download citation: RISBibTeXText

PMID: 7251405


Related references

Oral mucoceles; extravasation cysts and retention cysts. A study of 298 cases. Swedish Dental Journal 33(3): 125-130, 2009

Mucoceles of minor salivary glands. Acta Stomatologica Croatica 14(3-4): 90-96, 1980

Mucoceles of minor salivary glands in children. Own clinical observations. Developmental Period Medicine 20(3): 235-242, 2017

Myofibroblasts in mucoceles and chronic sialadenitis of minor salivary glands. Hippokratia 15(4): 382-383, 2011

Combination of postoperative ethmoidal mucoceles with other sinal mucoceles a report of 5 cases. Jibi Inkoka Tokeibu Geka 63(2): 111-114, 1991

Proteolytic enzymes in salivary extravasation mucoceles. Journal of Oral Pathology & Medicine 24(7): 299-302, 1995

Bronchial Atresia With Mucoceles and Concurrent Sinus Mucoceles. Clinical Pulmonary Medicine 15(2): 122-125, 2008

Retrocecal mucus-secreting tumors of the appendix (mucoceles). Apropos of 3 radiologically diagnosed cases. Journal de Radiologie 69(12): 741-750, 1988

Retention mucoceles of the oral mucosa. Journal of Oral Pathology 3(4): 197-202, 1974

Canine ranulas, salivary mucoceles and branchial cysts. Journal of Small Animal Practice 7(10): 625-630, 1966

Post-traumatic sialoceles and mucoceles of the salivary glands. Clinical Imaging 17(1): 41-45, 1993

Significant correlation between matrix metalloproteinase activity and tumor necrosis factor-alpha in salivary extravasation mucoceles. Journal of Oral Pathology & Medicine 27(1): 30-33, 1998

Sclerotherapy for the mucoceles of the anterior lingual salivary glands with pingyangmycin. Oral Diseases 20(5): 473-476, 2015

Surgery of mucoceles in the paranasal sinuses, with retention of the mucous membrane. Orvosi Hetilap 96(41): 1140-1142, 1955

Microwave Ablation: A Novel Treatment for the Mucoceles of Anterior Lingual Salivary Glands. Journal of Oral and Maxillofacial Surgery 75(3): 530-535, 2016