Mycoplasma hyorhinis swine arthritis. I. Clinical and microbiologic features
Barden, J.A.; Decker, J.L.
Arthritis and Rheumatism 14(2): 193-201
ISSN/ISBN: 2326-5191 PMID: 4101208 DOI: 10.1002/art.1780140202
An acute arthritis is followed in 6 to 8 months by the development of chronic polyarthritis when young Yorkshire swine are given a single intraperitoneal inoculation of Mycoplasma hyorhinis. Sequential antibody studies, using the metabolic inhibition test, revealed a brisk response in infected animals followed by sustained elevations of titers. Synovial fluid titers were found to exceed those of serum, suggesting local antibody production. The organism, readily recovered in the acute phase, became progressively more difficult to isolate.