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Platelet monoamine oxidase and clinical phenomenology of schizophrenia



Platelet monoamine oxidase and clinical phenomenology of schizophrenia



Psychiatry Research 11(3): 205-209



Platelet monoamine oxidase activity (MAO) was determined in 39 unmedicated chronic schizophrenic patients and 88 normal control subjects. Platelet MAO activity did not distinguish paranoid from nonparanoid patients or patients who met Taylor and Abrams criteria for narrowly defined schizophrenia from other schizophrenics. Enzyme activity was not related to either prognostic scores or age at onset of illness. MAO activity was decreased in patients compared to controls, and was lower in males than in females. Our findings indicate that clinical phenomenology, as defined in the present study, is of limited use in identifying biological subtypes of schizophrenia with deviant platelet MAO activity.

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Accession: 043965606

Download citation: RISBibTeXText

PMID: 6587413

DOI: 10.1016/0165-1781(84)90069-6


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