EurekaMag.com logo
+ Site Statistics
References:
48,253,228
Abstracts:
22,798,842
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
EurekaMag PDF Full Text Supply ServicePDF Full Text Supply Service
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn
Follow on LinkedInFollow on Tumblr

+ Translate

Regulation of L-phenylalanine ammonia-lyase by L-phenylalanine and nitrogen in Neurospora crassa


, : Regulation of L-phenylalanine ammonia-lyase by L-phenylalanine and nitrogen in Neurospora crassa. Journal of Bacteriology 150(3): 1287-1291

Neurospora crassa possesses an inducible L-phenylalanine ammonia-lyase that is expressed only when cells are derepressed for nitrogen in the presence of L-phenylalanine. Enzyme synthesis requires both induction by L-phenylalanine and simultaneous nitrogen catabolite derepression. Carbon limitation in the presence of phenylalanine does not elicit induction of L-phenylalanine ammonia-lyase. Specific induction by L-phenylalanine is required, and other amino acids completely failed to induce any lyase activity. The nit-2 gene is a major regulatory locus which is believed to mediate nitrogen catabolite repression in Neurospora. Mutants of nit-2 fail to express any phenylalanine ammonia-lyase activity under conditions of derepression and induction which lead to good enzyme induction in the wild type and in nit-2 revertants. The loss of lyase activity in nit-2 mutants does not result from inducer exclusion, which suggests that the nit-2 gene product has a direct role in controlling the expression of this enzyme. Substantial amounts of the enzyme were detected in the growth medium as well as in cell extracts. Inhibitors of protein synthesis or RNA synthesis block the induction of L-phenylalanine ammonia-lyase, suggesting that expression of this enzyme is controlled at the level of transcription.

(PDF 0-2 workdays service)

Order PDF Full Text

Close
Close

Click here to order any other PDF Full Text


Accession: 044172924

PMID: 6210688

PDF Full Text: Submit


Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:
Close
Close

Other references

Curtis, Quin Fischer, 1960: The effect of floor cues upon the mastery of the unit-alike maze. Dissertation Absts 20(8): 3397

Pang XiaoMing; Deng XiuXin; Hu ChunGen, 2003: Construction of AFLP fingerprint of 36 Poncirus accessions. An amplified fragment length polymorphism (AFLP) analysis system was established for distinguishing different Poncirus accessions. Seven primer pairs with high polymorphism were screened from 40 primer pairs. The screened subset of primer pairs pr...

Palmer J.M., 1984: The mechanisms and regulation of malate oxidation in isolated plant mitochondria. Physiologie Vegetale 22(5): 665-674

You, X.; Gao, L.; Liu, J.; Xu, C.; Liu, C.; Li, Y.; Hui, N.; Gu, H.; Ni, X., 2012: CRH activation of different signaling pathways results in differential calcium signaling in human pregnant myometrium before and during labor. Our previous study has demonstrated that CRH has differential effects on human uterine contractility before and after onset of labor. Intracellular Ca<sup>2+</sup> concentration ([Ca<sup>2+</sup>]i) mobilization plays an im...

Merrill, W.; French, D. W., 1966: Decay in wood and wood fiber products by Sporotrichum pruinosum. Sporotrichum pruinosum isolated from fiberboard in a roof deck is assumed to have caused the deterioration of the wood fiber. S. pruinosum which grows at temperatures from 10[degree] to 50[degree]C, grows most rapidly on agar at 35[degree] and 38o...

Isaac, V.; Lillie, E.W., 1972: Amniotic fluid creatinine and birth weight in normal and toxaemic pregnancies. Journal of the Irish Medical Association 65(1): 9-12

Mccosker J.E., 1985: Two new genera and two new species of deepwater western atlantic worm eels pisces ophichthidae. Two new genera and two new species of Atlantic worm eels, family Ophichthidae, subfamily Myrophinae, tribe Myrophini, are described and illustrated. Mixomyrophis pusillipinna, gen. nov., sp. nov., trawled from deep water off the Lesser Antilles [A...

Burnay, LP. da Conceicao, B., 1984: Contribuicao para o estudo da fauna malacologica do arquipelago de Cabo Verde. Familia Olividae (Mollusca: Gastropoda). Garcia De Orta Serie de Zoologia. 1983- ; 111-2: 25-40

Shuvaev, Vladimir V.; Laffont, Isabelle; Serot, Jean Marie; Fujii, Junichi; Taniguchi, Naoyuki; Siest, Gerard, 2001: Increased protein glycation in cerebrospinal fluid of Alzheimer's disease. Accumulation of advanced glycation end products occurs in the brain with ageing and was proposed to be involved in pathogenesis of Alzheimer's disease. We studied changes in the level of an early glycation product, an Amadori product, in cere...

Scotford, Im; Miller, Pch, 2004: Combination of spectral reflectance and ultrasonic sensing to monitor the growth of winter wheat. A preliminary study is reported in which a two channel (660 and 730 nm wavelength) radiometer system and ultrasonic sensor were attached to a tractor mounted boom and used in parallel to measure the normalised difference vegetation index (NDVI) an...