EurekaMag.com logo
+ Translate

Regulation of gene function: a comparison of X-linked enzyme activity levels in normal and intersexual triploids of Drosophila melanogaster


, : Regulation of gene function: a comparison of X-linked enzyme activity levels in normal and intersexual triploids of Drosophila melanogaster. Genetics 73(3): 459-464

We have measured gene function in normal and male-like intersexual triploids of Drosophila melanogaster by assaying crude extracts of whole flies or thoraces for levels of an X-linked (6-phosphogluconate dehydrogenase) and an autosomal (NADP-dependent isocitrate dehydrogenase) enzyme activity. Our observations lead us to conclude that each dose of the X-linked gene is more active in the cells of these intersexes than it is in normal triploid or diploid female cells. These results indicate that a level of activity intermediate between the normal male and female levels is possible for X-linked genes.

(PDF 0-2 workdays service)

Accession: 044174123

PMID: 4144727

Submit PDF Full Text: Here


Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:
Close
Close

Related references

Lucchesi, J.C.; Rawls, J.M., 1973: Regulation of gene function: a comparison of enzyme activity levels in relation to gene dosage in diploids and triploids of Drosophila melanogaster. Biochemical Genetics 9(1): 41-51

Lucchesi, J.C.; Rawls, J.M.Jr, 1973: Regulation of gene function a comparison of x linked enzyme activity levels in normal and inter sexual tri ploids of drosophila melanogaster. Genetics 73(3): 459-464

Lucchesi, J.C.; Rawls, J.M.Jr, 1973: Regulation of gene function a comparison of enzyme activity levels in relation to gene dosage in di ploids and tri ploids of drosophila melanogaster. Biochemical Genetics 9(1): 41-51

Maroni, Gustavo-Primo, 1973: Dosage compensation and gene regulation in Drosophila melanogaster triploids and diploids

Sampsell, B.; Steward, E., 1983: Alcohol dehydrogenase thermostability variants in Drosophila melanogaster: comparison of activity ratios and enzyme levels. Representatives of five allozymic classes of Drosophila alcohol dehydrogenase have been compared with respect to their activity levels on two alcohol substrates, quantities of ADH protein, and stability in crude extracts. Within each allozymic cla...

Triantaphyllidis C.D.; Panourgias J.N.; Scouras Z.G.; Ioannidis G.C., 1980: A comparison of gene enzyme variation between drosophila melanogaster and drosophila simulans. Genetic variation at 11 gene loci coding for enzymes was studied in sympatric Greek island populations of D. melanogaster and D. simulans. Only 2 enzyme loci indicate an absolute interspecific difference. In D. melanogaster, the average number of...

Berger, E.M., 1970: A comparison of gene enzyme variation between drosophila melanogaster and drosophila simulans. Genetics 66(4): 677-683

Nandy, B.; Gupta, V.; Udaykumar, N.; Samant, M.A.; Sen, S.; Prasad, N.G., 2014: Experimental evolution of female traits under different levels of intersexual conflict in Drosophila melanogaster. A number of studies have documented the evolution of female resistance to mate-harm in response to the alteration of intersexual conflict in the populations. However, the life-history consequence of such evolution is still a subject of debate. In...

Maroni, G.; Plaut, W., 1973: Dosage Compensation in DROSOPHILA MELANOGASTER Triploids. II. Glucose-6-Phosphate Dehydrogenase Activity. The level of activity of the enzyme glucose-6-phosphate dehydrogenase was determinel in flies having seven different chromosomic constitutions. All those having an integral number of chromosomes [XAA, XXAA, XAAA, XXAAA, and XXXAAA (X=Xchromosome,...

Maroni, G.P.aut, W., 1973: Dosage compensation in Drosophila melanogaster triploids. II. Glucose-6-phosphate dhydrogenase activity. Genetics 74 (2) 331-342