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Regulation of genes coding for enzyme constituents of the bacterial phosphotransferase system


, : Regulation of genes coding for enzyme constituents of the bacterial phosphotransferase system. Journal of Bacteriology 141(2): 658-663

Regulation of the synthesis of the proteins of the phosphoenolpyruvate:sugar phosphotransferase system was systematically studied in wild-type and mutant strains of Salmonella typhimurium and Escherichia coli. The results suggest that enzyme I and HPr as well as the glucose-specific and the mannose-specific enzymes II are synthesized by a mechanism which depends on (i) cyclic adenosine monophosphate and its receptor protein; (ii) extracellular inducer; (iii) the sugar-specific enzyme II complex which recognizes the inducing sugar; and (iv) the general energy-coupling proteins of the phosphotransferase system, enzyme I and HPr.

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Accession: 044174126

PMID: 6245053

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